Clean and Facile Condensations Reaction of Indoles and Carbonyl Compounds Under Solvent-Free Conditions

Authors: Mehrazma, Shokoufeh; Azizi, Najmoddin; Saidi, Mohammad R.

Source: Letters in Organic Chemistry, Volume 3, Number 2, February 2006 , pp. 161-164(4)

Publisher: Bentham Science Publishers

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Abstract:

A simple, rapid, atom economy and highly efficient green protocol has been developed for the reactions of indole with carbonyl compounds under solvent- free conditions. The attractive features of these procedures are the mild reaction conditions, high conversions, cleaner reaction profiles, inexpensive and environmentally friendly lithium perchlorate and short reaction times.

Keywords: bis indole; indole; carbonyl compounds; lithium perchlorate; atom economy

Document Type: Research article

Affiliations: 1: Department of Chemistry, Sharif University of Technology, P. O. Box 11465-9516 Terhran, Iran.

Publication date: 2006-02-01

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