Green Route to the 2,6-Disubstituted Imidazo[2,1-b]-1,3,4-Thiadiazoles by the Cyclocondensation of α-Bromoacetophenone Derivative and 1,3,4- Thiadiazoles Using Ionic Liquids
Authors: Kidwai, Mazaahir; Rastogi, Shweta
Source: Letters in Organic Chemistry, Volume 3, Number 2, February 2006 , pp. 149-152(4)
Publisher: Bentham Science Publishers
Abstract:An eco-friendly facile synthesis of imidazo[2,1-b]-1,3,4-thiadiazoles is described using ionic liquid, [bmim]PF6 (1-butyl-3-methylimidazolium hexafluorophosphate). The use of recyclable catalyst demonstrates the advantages of significant rate enhancement along with improved yields. The protocol is green and effective for producing the desired target moiety.
Document Type: Research Article
Affiliations: Department of Chemistry, University of Delhi, Delhi-110007, India.
Publication date: February 2006
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