Three Components Coupling Catalysed by Na2CaP2O7: Synthesis of α-Amino Phosphonates Under Solvent-Free Conditions at Room Temperature
Synthetic phosphate Na2CaP2O7 has been utilized as an efficient catalyst for the three components coupling of carbonyl compounds, aromatic and aliphatic amines and dialkyl phosphite to produce α-amino phosphonates. The reaction was carried out under solvent-free conditions at room temperature. The by-product H2O formed during the reaction increases the catalytic activity of Na2CaP2O7.
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Document Type: Review Article
Affiliations: Laboratoire de Catalyse, Chimiometrie et Environnement, UFR de Chimie Appliquee, Faculte des Sciences et Techniques, Universite Hassan II, Mohammedia B. P. 146, 20650 Maroc.
Publication date: 2005-08-01
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