Three Components Coupling Catalysed by Na2CaP2O7: Synthesis of α-Amino Phosphonates Under Solvent-Free Conditions at Room Temperature
Abstract:Synthetic phosphate Na2CaP2O7 has been utilized as an efficient catalyst for the three components coupling of carbonyl compounds, aromatic and aliphatic amines and dialkyl phosphite to produce α-amino phosphonates. The reaction was carried out under solvent-free conditions at room temperature. The by-product H2O formed during the reaction increases the catalytic activity of Na2CaP2O7.
Document Type: Review Article
Affiliations: Laboratoire de Catalyse, Chimiometrie et Environnement, UFR de Chimie Appliquee, Faculte des Sciences et Techniques, Universite Hassan II, Mohammedia B. P. 146, 20650 Maroc.
Publication date: August 1, 2005
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