Enzymatic Oxidation of 1,4- and 1,8-Cineole using Plant Cultured Cells of Catharanthus Roseus
Abstract:Oxidases present in plant cultured cells of Catharanthus roseus can hydroxylate saturated centers of natural products without double bond activation. When starting materials were 1,8- or 1,4-cineole, secondary and tertiary alcohols were produced and identified using NMR and mass spectroscopy. Our results indicate that hydroxylation position and stereochemistry are determined by the biotransformation organism.
Document Type: Review Article
Affiliations: Department of Applied Science, Okayama University of Science, 1-1 Ridai-cho, Okayama 700- 0005, Japan.
Publication date: 2004-04-01
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