Synthesis and Reactivity of α-Halogenated, C-Protected β-Enamino Acids
C-Protected β-enamino acids (I) reacted with one equivalent of Nhalosuccinimides (NXS) to furnish their α-halogenated derivatives (II). These compounds were then successfully transformed into halogenated uracil derivatives (III) through reaction with triphosgene, followed by 5-membered ring-opening under acidic conditions.
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Document Type: Review Article
Affiliations: Departamento de Quimica Organica, Universidad de Valencia, E-46100 Burjassot, Spain.
Publication date: 2004-04-01
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