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Letters in Drug Design & Discovery publishes original letters on all areas of rational drug design and discovery including medicinal chemistry, in-silico drug design, combinatorial chemistry, high-throughput screening, drug targets, and structure-activity relationships. The emphasis will be on publishing quality papers very rapidly. Letters will be processed rapidly by taking full advantage of Internet technology for both the submission and review of manuscripts. The journal is essential reading to all pharmaceutical scientists involved in research in drug design and discovery.

Publisher: Bentham Science Publishers

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Volume 6, Number 8, December 2009

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Articles

QSAR Study of Androstenedione Analogs as Aromatase Inhibitors
pp. 554-562(9)
Authors: Oliveira, Aline A.; Ramalho, Teodorico C.; da Cunha, Elaine F.F.

Pretreatment with Huperzine A Protects Acetylcholinesterase in the Rat Brain Against Inhibition by VX and Russian VX
pp. 563-567(5)
Authors: Karasova, Jana Z.; Bajgar, Jiri; Novotny, Ladislav; Kuca, Kamil

3D-QSAR Study of Synthetic Furanones as Inhibitors of Quorum Sensing by Using CoMFA and CoMSIA Approach
pp. 568-574(7)
Authors: Sun, Ping-Hua; Yang, Zhao-Qi; Li, Mao-Kang; Chen, Wei-Min; Liu, Qian; Yao, Xin-Sheng

Design and Synthesis of Pterin Derivares as Nitric Oxide Synthase Inhibitors
pp. 575-578(4)
Authors: Ma, Fei; Guo, Ping; Jiang, Lixun; Feng, Mingsheng; Shi, Jingbo; Yao, Qizheng

Computer-Aided Drug Design of Pyranopyrazoles and Related Compounds for Checkpoint Kinase-1
pp. 579-584(6)
Authors: Ramtekkar, Rahul; Kumarvel, Kandhasamy; Vasuki, Gnanasambandam; Sekar, K.; Krishna, R.

H3 Receptor Antagonists: Pharmacophore Modeling and its Implications (Supplementry Material)
pp. 585-594(10)
Authors: Pramod, A. B.; Sindiri, Sivasish; Nayana, M. R.S.; Bairy, Santhosh K.; Ananthula, Ravi S.h.e.k.a.r.; Muttineni, Ravikumar; Srividya, Madala; Kumar, M. K.i.s.h.o.r.e.

Design, Synthesis and Antiproliferative Activities of Artemisinin Derivatives Containing a Substituted Piperazine
pp. 595-598(4)
Authors: Yang, Xue-Lin; Liu, Dan; Wang, Wei; Qu, Lei; Jing, Yong-Kui; Zhao, Lin-Xiang

Identification of Potential Drug Targets of Leishmania infantum by In-silico Genome Analysis
pp. 620-622(3)
Authors: Suthar, Neeraj; Goyal, Arun; Dubey, Vikash K.

Synthesis and Biological Evaluation of 5,6-Dihydro-benzo[c] acridin-7-ol Derivatives as Anti-Alzheimer's Disease Drugs
pp. 623-628(6)
Authors: Zhou, Jinpei; Hu, Xiaowen; Zhang, Huibin; Qian, Hai; Huang, Wenlong; Qi, Fan; Zhang, Yanchun

Determination of Interchangeability of Different Brands of Diclofenac Sodium Sustained Release Tablets in Healthy Subjects Using Pharmacokinetic End Points
pp. 629-636(8)
Authors: Wani, Tanveer A.; Samad, Abdus; Sharma, P. L.; Tandon, Monika; Paliwal, J. K.

Synthesis and Characterization of Substituted Ethyl 2-(1-aminocyclobutyl)- 5-(benzoyloxy)-6-hydroxypyrimidine-4-carboxylate Derivatives as Antioxidant Agents
pp. 637-643(7)
Authors: Asha, D.; Malviya, Manish; Chandrappa, S.; Sadashiva, C. T.; Vinaya, K.; Prasanna, D. S.; Rangappa, K. S.

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