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Letters in Drug Design & Discovery publishes original letters on all areas of rational drug design and discovery including medicinal chemistry, in-silico drug design, combinatorial chemistry, high-throughput screening, drug targets, and structure-activity relationships. The emphasis will be on publishing quality papers very rapidly. Letters will be processed rapidly by taking full advantage of Internet technology for both the submission and review of manuscripts. The journal is essential reading to all pharmaceutical scientists involved in research in drug design and discovery.

Publisher: Bentham Science Publishers

Volume 6, Number 7, October 2009
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Articles

Solification with Hydrobromic Acid as a Factor Defining the Antiarrhythmic Effect of Lappaconitine Derivatives
pp. 475-477(3)
Authors: Tolstikova, T. G.; Bryzgalov, A. O.; Sorokina, I. V.; Osadchii, S. A.; Shults, E. E.; Dolgikh, M. P.; Khvostov, M. V.

Synthesis and Biological Evaluation of Bridged Analogues of the Platelet Aggregation Inhibitor Trifenagrel
pp. 478-486(9)
Authors: Slusarczyk, Magdalena; De Borggraeve, Wim M.; Hoornaert, Georges; Robeyns, Koen; Meervelt, Luc V.; Wu, Tongfei; Deroose, Frederik; Linders, Joannes T.M.

Targeting the Peptide Deformylase of Mycobacterium tuberculosis Leads to Drug Discovery
pp. 487-493(7)
Authors: Singh, Vijai; Somvanshi, Pallavi

In Silico Screening of Novel Inhibitors for HPV: A Rational Structure Based Approach (Docking Versus Pharmacophore Model Generation)
pp. 494-501(8)
Authors: Reshmi, G.; Pillai, M. R.

Microwave-Assisted Solvent-Free Synthesis of N-alkyl Benzotriazole Derivatives: Antimicrobial Studies
pp. 502-507(6)
Authors: Ningegowda, Raghu; Kavitha, C. V.; Priya, B. S.; Gaonkar, S. L.; Tejesvi, M. V.; Rangappa, K. S.; Swamy, S. N.

New Pyrrole Hydrazones Synthesized and Evaluated In Vitro as Potential Tuberculostatics
pp. 508-517(10)
Authors: Bijev, A.; Vladimirova, S.; Prodanova, P.

Synthesis and Biochemical Evaluation of a Series of Methanesulfonate Derivatives of 4-Hydroxyphenyl Ketone as Probes of the Active Site of Type 3 OF 17β-Hydroxysteroid Dehydrogenase Family of Enzymes
pp. 518-523(6)
Authors: Shah, Kruti; Olusanjo, Moniola S.; Cartledge, Tim; Owen, Caroline P.; Ahmed, Sabbir

Synthesis and Biochemical Evaluation of a Range of 2-, 3- and 4-Substituted Derivatives of Benzyl Imidazole-Based Compounds as Probes of the Active Site of 17α-hydroxylase/17,20-Lyase (P45017α)
pp. 524-530(7)
Authors: Ahmed, Sabbir; Shahid, Imran; Bhatti, Kishore K.; Lee, Wai-Yee; Owen, Caroline P.

On the Synthesis and Anticancer Testing of α,β-Unsaturated Ketones as Analogs of Combretastatin-A4
pp. 531-537(7)
Authors: Chavda, Sameer; Davis, Ryan; Ferguson, Amanda; Riddering, Camille; Dittenhafer, Kristin; Mackay, Hilary; Babu, Balaji; Lee, Moses; Siegfried, Adam; Pennington, William; Shadfan, Miriam; Mooberry, Susan L.; Mishra, Bijay K.; Pati, Hari N.

Design, Synthesis, Crystal Structure and Antitumor Activity of A New Ethyl 3-(quinazolin-4-ylamino)-1H-pyrrole-2-carboxylate Derivative
pp. 538-541(4)
Authors: Zheng, Youguang; Wu, Xiaoqing; Sun, Min; Feng, Liuhai; Li, Mingdong; Ji, Min

Enhanced Brain Targeting of Tegafur Using Novel Lactyl Cholesterol Liposome as a Carrier
pp. 542-547(6)
Authors: Fan, Wei; Li, Xiankun; Qian, Shan; Wang, Shan; Wu, Yong

Synthesis, Anticonvulsant Evaluation of 2,3,4,5-Tetrahydro-7-alkoxy-1H-2-benzazepin-1-ones
pp. 548-553(6)
Authors: Wei, Cheng-Xi; Zhang, Wei; Quan, Zhe-Shan; Han, Rong-Bi; Jiang, Ri-Shan; Piao, Feng-Yu

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