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Letters in Drug Design & Discovery publishes original letters on all areas of rational drug design and discovery including medicinal chemistry, in-silico drug design, combinatorial chemistry, high-throughput screening, drug targets, and structure-activity relationships. The emphasis will be on publishing quality papers very rapidly. Letters will be processed rapidly by taking full advantage of Internet technology for both the submission and review of manuscripts. The journal is essential reading to all pharmaceutical scientists involved in research in drug design and discovery.

Publisher: Bentham Science Publishers

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Volume 6, Number 6, September 2009

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Articles

The Anticancer Activity of the N-Terminal CARD-Like Domain of Arginine Deiminase (ADI) from Pseudomonas aeruginosa
pp. 403-412(10)
Authors: Kundu, Madhuchhanda; Thomas, Johnson; Fialho, Arsenio M.; Kwan, Jennifer M.; Moreira, Leonilde M.; Mahfouz, Magdy; Das Gupta, Tapas K.; Chakrabarty, Ananda M.

Synthesis and Evaluation of Anthelmintic and Cytotoxic Properties of [2,5']Bis-1,3-Azole Analogs of Bengazoles
pp. 413-419(7)
Authors: Scarone, Laura; Fajardo, Jose; Saldana, Jenny; Dominguez, Laura; Esposito, Pablo; Demastteis, Sylvia; Wipf, Peter; Manta, Eduardo; Serra, Gloria

The Synthesis and Activity Evaluation of a Bestatin Derivative (LYP) as an Aminopeptidase N Inhibitor
pp. 420-423(4)
Authors: Luan, Yepeng; Wang, Xuejian; Zhu, Huawei; Qu, Xianjun; Fang, Hao; Xu, Wenfang

Synthesis and Bioactivities of 2-Azetidinones as Cholesterol Absorption Inhibitors
pp. 424-427(4)
Authors: Ji, Jianfeng; Zhao, Rui; Huang, Wenlong; Zhang, Huibin; Zhou, Jinpei; Wang, Yubin; Qian, Hai

Anti-Amyloid Effects of Small Molecule Aβ-Binding Agents in PS1/APP Mice
pp. 437-444(8)
Authors: Cohen, A. D.; Ikonomovic, M. D.; Abrahamson, E. E.; Paljug, W. R.; DeKosky, S. T.; Lefterov, I. M.; Koldamova, R. P.; Shao, L.; Debnath, M. L.; Mason, N. S.; Mathis, C. A.; Klunk, W. E.

Synthesis and Pharmacological Activity of Thiourea Derivatives of 1,7,8,9-Tetramethyl-4-azatricyclo[5.2.1.02,6]dec-8-ene-3,5-dione
pp. 445-450(6)
Authors: Struga, Marta; Kossakowski, Jerzy; Koziol, Anna E.; Lis, Tateusz; Kedzierska, Ewa; Fidecka, Sylwia

Anticonvulsant Activity of A Novel Series of 2,5-Disubstituted 1,3,4-Oxadiazoles: Semicarbazones Based Pharmacophoric Model Studies
pp. 456-463(8)
Authors: Rajak, Harish; Veerasamy, Ravichandran; Singour, Pradeep; Kharya, Murli D.; Mishra, Pradeep

8-(Trifluoromethyl)-1,2,3,4,5-benzopentathiepin-6-amine: Novel Aminobenzopentathiepine having In Vivo Anticonvulsant and Anxiolytic Activities
pp. 464-467(4)
Authors: Khomenko, Tatyana M.; Tolstikova, Tatyana G.; Bolkunov, Alexey V.; Dolgikh, Margarita P.; Pavlova, Alla V.; Korchagina, Dina V.; Volcho, Konstantin P.; Salakhutdinov, Nariman F.

Synthesis and Structure-Activity Relationship Study of 2-Substituted- 5-(5-nitro-2-thienyl)-1,3,4-thiadiazoles as Anti-Helicobacter pylori Agents
pp. 468-474(7)
Authors: Foroumadi, Alireza; Sedaghat, Somayeh; Emami, Saeed; Yazdanian, Maryam; Moshafi, Mohammad H.; Safavi, Maliheh; Sakhteman, Amirhossein; Firoozpour, Loghman; Vosooghi, Mohsen; Shafiee, Abbas

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