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Letters in Drug Design & Discovery publishes original letters on all areas of rational drug design and discovery including medicinal chemistry, in-silico drug design, combinatorial chemistry, high-throughput screening, drug targets, and structure-activity relationships. The emphasis will be on publishing quality papers very rapidly. Letters will be processed rapidly by taking full advantage of Internet technology for both the submission and review of manuscripts. The journal is essential reading to all pharmaceutical scientists involved in research in drug design and discovery.

Publisher: Bentham Science Publishers

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Volume 5, Number 7, 2008

Articles

Synthesis, DNA-Binding Ability and Biological Activity of C8 Linked G1 Dendrimer-Pyrrolobenzodiazepine Conjugates as Anticancer Agents
pp. 424-432(9)
Authors: Kamal, Ahmed; Balakishan, G.; Rajender; Sreekanth, K.; Reddy, D. R.; Reddy, M. Kashi; Sen, Subrata; Kurian, Nisha; Juvekar, Aarti S.; Zingde, Surekha M.

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Sesquiterpene Lactones and their Anti-Tumor Activity from the Flowers of Inula Britannica
pp. 433-436(4)
Authors: Qi, Jin-Long; Fu, Yan; Shi, Xiao-Wei; Wu, Yi-Bing; Wang, Yun-Zhi; Zhang, Di-Qun; Shi, Qing-Wen

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3D-QSAR Analysis on N-Phenylacetanoyl-L-Homoserine Lactones as Inhibitors of Bacterial Quorum Sensing via CoMFA Approach
pp. 449-453(5)
Authors: Sun, Ping-Hua; Yang, Zhao-Qi; Chen, Wei-Min; Liu, Qian; Yao, Xin-Sheng

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Synthesis and In Vitro Antiproliferative Activity of Diphenyl(piperidin-4- yl)thioamide Methanol Derivatives
pp. 454-461(8)
Authors: Benaka Prasad, Salekoppal B.; Vinaya, Mallappanahally Kambappa; Ananda Kumar, Channapille K. S.; Swarup, Sanjay; Rangappa, Kanchugarakoppal Subbegowda

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Release of a Poorly Soluble Drug from Cross-Linked β-Cyclodextrin-Based Polymer Pellets Prepared via Extrusion/Spheronisation
pp. 462-470(9)
Authors: Bon, Pierre; Joudieh, Samer; Lahiani-Skiba, Malika; Bounoure, Frederic; Dechelotte, Pierre; Skiba, Mohamed

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96-Well Plate Surface Tension Measurements for Fast Determination of Drug Solubility
pp. 471-476(6)
Authors: Heikkila, Tiina; Peltonen, Leena; Taskinen, Saila; Laaksonen, Timo; Hirvonen, Jouni

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