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Letters in Drug Design & Discovery publishes original letters on all areas of rational drug design and discovery including medicinal chemistry, in-silico drug design, combinatorial chemistry, high-throughput screening, drug targets, and structure-activity relationships. The emphasis will be on publishing quality papers very rapidly. Letters will be processed rapidly by taking full advantage of Internet technology for both the submission and review of manuscripts. The journal is essential reading to all pharmaceutical scientists involved in research in drug design and discovery.

Publisher: Bentham Science Publishers

Volume 4, Number 5, July 2007

Articles

The Therapeutic Potential of Gallium-Based Complexes in Anti-Tumor Drug Design
pp. 311-317(7)
Authors: Frezza, Michael; Verani, Claudio N.; Chen, Di; Dou, Q. Ping

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Stereochemistry as a Determinant of the Anti-Leukemic Potency of Halopyridyl and Thiazolyl Thiourea Compounds
pp. 318-326(9)
Authors: Venkatachalam, Taracad K.; Vassilev, Alexi O.; Benyunov, Alexi; Grigoriants, Olga O.; Tibbles, Heather E.; Uckun, Fatih M.

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Synthesis and Chemical Characterization of N10-Substituted Acridones as Reversers of Multidrug Resistance in Cancer Cells
pp. 327-335(9)
Authors: Mayur, Y.C.; Gouda, Manjunath; Gopinath, Vadiraj S.; Shanta Kumar, S.M.; Rajendra Prasad, V.V.S.

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The Tumor Necrosis Factor-Derived TIP Peptide: A Potential Anti-Edema Drug
pp. 336-340(5)
Authors: Lucas, Rudolf; Hundsberger, Harald; Pfluger, Maren; Fischer, Bernhard; Morel, Denis; Braun, Clemens; Wendel, Albrecht; Chakraborty, Trinad; Schutt, Wolfgang; Wiesner, Christoph; Hamacher, Jurg

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Synthesis and Cytotoxic Activity of Cisplatin Analogue with an Ursodeoxycholate Ligand
pp. 341-345(5)
Authors: Perez-Andres, Martin; Jose Benito, Juan; Rodriguez-Fernandez, Emilio; Luis Manzano, Juan; Barrena, Susana; Orfao, Alberto; Jose Criado, Julio

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Molecular Basis of Agonistic Activity of ERα17p, a Synthetic Peptide Corresponding to a Sequence Located at the N-Terminal Part of the Estrogen Receptor αLigand Binding Domain
pp. 346-355(10)
Authors: Gallo, Dominique; Jacquot, Yves; Cleeren, Anny; Jacquemotte, Francoise; Laios, Ioanna; Laurent, Guy; Leclercq, Guy

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Hologram Quantitative Structure-Activity Relationships for a Class of Inhibitors of HIV-1 Protease
pp. 356-364(9)
Authors: Ferreira, Leonardo G.; Leitao, Andrei; Montanari, Carlos A.; Andricopulo, Adriano D.

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Design of Molecules Acting on the Serotonin Receptors
pp. 365-367(3)
Authors: Saturnino, Carmela; Buonerba, Mariafrancesca; Capasso, Anna

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Intracerebroventricular Injection of Glutathione-Related Dipeptides Induces Sedative and Hypnotic Effects During Acute Stress in Neonatal Chicks
pp. 368-372(5)
Authors: Yamane, Haruka; Suenaga, Rie; Han, Li; Hayamizu, Kohsuke; Denbow, D. Michael; Furuse, Mitsuhiro

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Nicotinic and Glycinergic Medications for Disorders of Hedonic Regulation
pp. 373-381(9)
Authors: Dyer, M.A.; Barr, R.S.; Evins, A.E.

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Synthesis and Biological Activities of New Triphenyl Organotin (IV) Based on the Pyrazole Carboxylic Acids
pp. 382-385(4)
Authors: Yahyi, Abderrahmane; Ettouhami, Abdelkader; Radi, Smaail; Zidane, Ismail; Hakkou, Abdelkader; Bouakka, Mohamed

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