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Letters in Drug Design & Discovery publishes original letters on all areas of rational drug design and discovery including medicinal chemistry, in-silico drug design, combinatorial chemistry, high-throughput screening, drug targets, and structure-activity relationships. The emphasis will be on publishing quality papers very rapidly. Letters will be processed rapidly by taking full advantage of Internet technology for both the submission and review of manuscripts. The journal is essential reading to all pharmaceutical scientists involved in research in drug design and discovery.

Publisher: Bentham Science Publishers

Volume 4, Number 3, April 2007
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Articles

Galloyl Group is not Necessary for a Sedative Effect of Catechin Through GABAergic System
pp. 163-167(5)
Authors: Adachi, Nami; Tomonaga, Shozo; Suenaga, Rie; Michael Denbow, D.; Furuse, Mitsuhiro

Increase in Pharmacological Activity of Drugs in their Clathrates with Plant Glycosides
pp. 168-170(3)
Authors: Tolstikova, T. G.; Bryzgalov, A. O.; Sorokina, I. V.; Hvostov, M. V.; Ratushnyak, A. S.; Zapara, T. A.; Simonova, O. G.

Synthesis and Preliminary Biological Evaluation of Estrone Dimers
pp. 171-174(4)
Authors: Rabouina, Daniel; Perrona, Valerie; N'Zemba, Blaise; Guptaa, Atul; Gaudreault, Rene-C.; Berube, Gervais

Design, Synthesis and Photodynamic Antimicrobial Activity of Ruthenium Trischelate Diimine Complexes
pp. 175-179(5)
Authors: Donnelly, R. F.; Fletcher, N. C.; McCague, P. J.; Donnelly, J.; McCarron, P. A.; Tunney, M. M.

Search for Potential Non-Steroidal Inhibitors of 17 β-Hydroxysteroid Dehydrogenase (17 β-HSD) in the Treatment of Hormone-Dependent Cancers
pp. 180-184(5)
Authors: Lota, Rupinder K.; Dhanani, Sachin; Owen, Caroline P.; Ahmed, Sabbir

Novel, Acidic CCR2 Receptor Antagonists: From Hit to Lead
pp. 185-191(7)
Authors: Zou, D.; Zhai, H.-X.; Eckman, J.; Higgins, P.; Gillard, M.; Knerr, L.; Carre, S.; Pasau, P.; Collart, P.; Grassi, J.

Rapid Classification of CYP3A4 Inhibition Potential Using Support Vector Machine Approach
pp. 192-200(9)
Authors: Zhou, Diansong; Liu, Ruifeng; Otmani, Sara A.; Grimm, Scott W.; Zauhar, Randy J.; Zamora, Ismael

Synthesis and Antitumor Activity of Novel Pentacyclic Triterpenoid Lantadene D
pp. 201-206(6)
Authors: Sharma, Manu; Dev Sharma, Pritam; Pal Bansal, Mohinder; Singh, Jaswant

The Role of Muscarinic Receptors in the Control of Acute Opioid Withdrawal
pp. 207-211(5)
Author: Capasso, Anna

A New 1,2,4-Triazole Acyclonucleosides: Synthesis and Biological Evaluation
pp. 212-214(3)
Authors: Radi, Smaail; Lazrek, Hassan B.

Maximizing the Identification of Leads from Compound Mixtures
pp. 215-223(9)
Authors: Warrior, Usha; Gopalakrishnan, Sujatha M.; Traphagen, Linda; Freiberg, Gail; Towne, Danli; Humphrey, Patrick; Kofron, James; Burns, David J.

mTOR Inhibition in Lymphoma: A Rational and Promising Strategy
pp. 224-231(8)
Authors: Smith, Sonali M.; van Besien, Koen

Synthesis and Binding Properties of New Endothelin Receptor Ligands
pp. 232-238(7)
Authors: Modica, Maria; Salerno, Loredana; Pittala, Valeria; Romeo, Giuseppe; Siracusa, Mariangela; Mereghetti, Ilario; Cagnotto, Alfredo; Mennini, Tiziana

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