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Letters in Drug Design & Discovery publishes original letters on all areas of rational drug design and discovery including medicinal chemistry, in-silico drug design, combinatorial chemistry, high-throughput screening, drug targets, and structure-activity relationships. The emphasis will be on publishing quality papers very rapidly. Letters will be processed rapidly by taking full advantage of Internet technology for both the submission and review of manuscripts. The journal is essential reading to all pharmaceutical scientists involved in research in drug design and discovery.

Publisher: Bentham Science Publishers

Volume 3, Number 2, March 2006
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Articles

Synthesis and Evaluation of Aminoglycosides as Inhibitors for Rev binding to Rev Responsive Element
pp. 71-75(5)
Authors: Adachi, Hayamitsu; Takahashi, Yoshinori; Kyo, Motoki; Sato, Tsuyoshi; Nishimura, Yoshio

Cannabinoids: Do they have a Role in Cancer Therapy?
pp. 76-82(7)
Authors: Liu, W. M.; Powles, Thomas B.

Synthesis and Antitumor Activity of 20-O-Linked Succinate-Based Camptothecin Ester Derivatives
pp. 83-86(4)
Authors: Lu, Hua; Lin, Haixia; Jiang, Yi; Zhou, Xinguang; Wu, Beili; Chen, Jianmin

Design, Synthesis, and Antibacterial Activity of Novel Carbacephems
pp. 91-97(7)
Authors: Moosavi-Movahedi, Ali A.; Yen, Chi-Feng; Chamani, Jamshid; Khodarahmi, Ghadam A.; Saboury, Ali A.; Hakimelahi, Gholam H.

Synthesis and Trypanocidal Evaluation of News 5-[N-(3-(5-Substituted)- 1,3,4-Thiadiazolyl)]Amino-1-Methyl-4-Nitroimidazoles
pp. 98-101(4)
Authors: Carvalho, A. S.; Gibaldi, D.; Pinto, A. C.; Bozza, M.; Boechat, N.

Homocystinuric Patient with Deficient CBS Activity: Pyridoxine Efficacy and Toxicity?
pp. 102-103(2)
Authors: Candito, M.; Dellamonica, P.; Hofman, P.; Obberghen, Emmanuel V.

CoMSIA/QSAR Models for Vacuolar (H+) ATPase Inhibition by Selected Benzoate and Benzolactone Species
pp. 104-107(4)
Authors: Blackman, Burchelle; Georg, Gunda I.; Lushington, Gerald H.

Benzenecarboxamide Analogs of Fluoroquinolones (BCFQs). Antibacterial Activity and SAR Studies
pp. 108-111(4)
Authors: Nieto, M. J.; Alovero, F. L.; Manzo, R. H.; Mazzieri, M. R.

Preparation and Biological Activity of Retinoic Acid Analogs Containing an Aromatic Ring
pp. 118-122(5)
Authors: Wada, Akimori; Mizuguchi, Yukari; Shinmen, Masaki; Ito, Masayoshi; Nakagawa, Kimie; Okano, Toshio

QSAR Study on Cytotoxic Activities of a Series of HEPT Analogues#
pp. 129-137(9)
Authors: Agrawal, Vijay K.; Singh, Jyoti; Mishra, K. C.; Khadikar, Padmakar V.

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