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Letters in Drug Design & Discovery publishes original letters on all areas of rational drug design and discovery including medicinal chemistry, in-silico drug design, combinatorial chemistry, high-throughput screening, drug targets, and structure-activity relationships. The emphasis will be on publishing quality papers very rapidly. Letters will be processed rapidly by taking full advantage of Internet technology for both the submission and review of manuscripts. The journal is essential reading to all pharmaceutical scientists involved in research in drug design and discovery.

Publisher: Bentham Science Publishers

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Volume 2, Number 7, November 2005

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Articles

Inhibitors of Hepatitis C Virus NS3.4A Protease: P2 Proline Variants
pp. 497-502(6)
Authors: Farmer, Luc J.; Britt, Shawn D.; Cottrell, Kevin M.; Court, John J.; Courtney, Lawrence F.; Deininger, David D.; Gates, Cynthia A.; Harbeson, Scott L.; Lin, Kai; Lin, Chao; Luong, Yu- P.; Maxwell, John P.; Pitlik, Janos; Rao, B. G.; Schairer, Wayne C.; Thomson, John A.; Tung, Roger D.; Van Drie, John H.; Wei, Yunyi; Perni, Robert B.

Ximelagatran: An Oral Direct Thrombin Inhibitor for Anticoagulant Therapy
pp. 503-506(4)
Authors: Rossi, Marco L.; Zavalloni, Dennis; Belli, Guido; Presbitero, Patrizia

Design of Selective Inhibitors of Tyrosine Kinase 2
pp. 507-515(9)
Authors: Tondel, Kristin; Drablos, Finn

Selectivity of SB203580, SB202190 and Other Commonly Used p38 Inhibitors: Profiling Against a Multi-Enzyme Panel
pp. 516-521(6)
Authors: Norris, Jacqueline L.; Williams, Kevin P.; Janzen, William P.; Hodge, C. N.; Blackwell, Leonard J.; Popa-Burke, Ioana G.

Synthesis and Anti-Breast Cancer Activity of Tetrasubstituted Pyrrole Derivatives
pp. 529-532(4)
Authors: Padron, Jose M.; Tejedor, David; Santos-Exposito, Alicia; Garcia-Tellado, Fernando; Villar, Jesus; Martin, Victor S.

New Peptidic GnRH Antagonists Offer a Broad Range of Therapeutic Applications
pp. 533-536(4)
Authors: Engel J.B,; Diedrich K,; Honig A,

Design Features that Affect Psychopharmacology Trials
pp. 546-550(5)
Authors: Khan, Arif; Schwartza, Kelly

A Review of the Regulatory Role of Nicotinamide on Pro- and Anti-apoptotic Proteins in Neuronal Cells
pp. 551-557(7)
Authors: Mukherjee, S. K.; Sonee, M.; J. D. Adams Jr,

L-Dopa Related Hyperhomocysteinemia: A Possible Mediator of Toxicity?
pp. 558-562(5)
Authors: Zoccolella, Stefano; Iliceto, Giovanni; deMari, Michele; Defazio, Giovanni; Livrea, Paolo; Lamberti, Paolo

Synthesis and Anti-Mycobacterial Activity of N'-[(E)-(Disubstituted- Phenyl)Methylidene]Isonicotino-Hydrazide Derivatives
pp. 563-566(4)
Authors: Junior, Ivan N.; Lourenco, Maria C.S.; Henriques, Maria das Gracas M.O.; Ferreira, Barbara; Vasconcelos, Thatyana R.A.; Peralta, Monica A.; de Oliveira, Pedro S.M.; Wardell, Solange M.S.V.; de Souza, Marcus V.N.

Interaction of Furosemide with the Human Sodium-Dependent Dicarboxylate Transporter (hNaDC-3)
pp. 567-570(4)
Authors: Muller, Ingo; Hagos, Yohannes; Burckhardt, Gerhard; Burckhardt, Birgitta C.

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