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Letters in Drug Design & Discovery publishes original letters on all areas of rational drug design and discovery including medicinal chemistry, in-silico drug design, combinatorial chemistry, high-throughput screening, drug targets, and structure-activity relationships. The emphasis will be on publishing quality papers very rapidly. Letters will be processed rapidly by taking full advantage of Internet technology for both the submission and review of manuscripts. The journal is essential reading to all pharmaceutical scientists involved in research in drug design and discovery.

Publisher: Bentham Science Publishers

Volume 2, Number 6, September 2005
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Addendum

Graphical Abstracts
pp. i-iv(4)

Review article

Thermodynamic Aspects of Cancer: Possible Role of Negative Entropy in Tumor Growth, its Relation to Kinetic and Genetic Resistance
pp. 429-438(10)
Authors: Molnar, Joseph; Thornton, Barry S.; Molnar, Annamaria; Gaal, Dezso; Luo, Liaofu; Bergmann-Leitner, Elke S.

Discovery, Structural Determination and Anticancer Activities of Lactucinlike Guaianolides
pp. 444-450(7)
Authors: Ren, Yulin; Zhou, Yawei; Chen, Xiaozhuo; Ye, Yunhua

Phenyldihydroxypyrimidines as HCV NS5B RNA Dependent RNA Polymerase Inhibitors. Part I: Amides and Ureas
pp. 451-455(5)
Authors: Crescenzi, B.; Poma, M.; Ontoria, J. M.; Marchetti, A.; Nizi, E.; Matassa, V. G.; Gardelli, C.

Phenyldihydroxypyrimidines as HCV NS5B RNA Dependent RNA Polymerase Inhibitors. Part II: Sulfonamides
pp. 456-461(6)
Authors: Ponzi, S.; Giuliano, C.; Donghi, M.; Poma, M.; Matassa, V. G.; Stansfield, I.

Micro Arrayed Compound Screening (mgrARCS) for Inhibitors of Methionine Aminopeptidase Type 2
pp. 462-469(8)
Authors: Fan, Yihong; Wang, Jieyi; Lou, Pingping; Henkin, Jack; Kofron, James L.; Burns, David J.; Warrior, Usha; Anderson, Steven N.

Antiretroviral Therapy: Is it the Right Time for New Strategies?
pp. 470-474(5)
Authors: Abrescia, N.; D'Abbraccio, M.; Busto, A.; Maddaloni, A.; Figoni, M.; De Marco, M.

Selection of a Catalytically Active Enzyme In Vivo Via Phage Display of its Product
pp. 475-478(4)
Authors: Taki, T.; Fujita, S.; Taira, K.

Redox Active Iron at the Center of Oxidative Stress in Alzheimer Disease
pp. 479-482(4)
Authors: Honda, Kazuhiro; Moreira, Paula I.; Liu, Quan; Siedlak, Sandra L.; Zhu, Xiongwei; Smith, Mark A.; Perry, George

Identifying Protein Binding Sites and Optimal Ligands
pp. 483-489(7)
Authors: Beuscher, Albert; Olson, Arthur J.; Goodsell, David S.

Immunomodulatory Properties of Synthetic Imidazolone Derivatives
pp. 490-496(7)
Authors: Mesaik, M. A.; Khan, K. M.; Rahat, S.; Zia-Ullah, Zia-Ullah; Choudhary, M. I.; Murad, S.; Abdullah, N. R.; Atta-ur-Rahman, Atta-ur-Rahman; Ahmad, A.; Siddiqui, R. A.

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