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Letters in Drug Design & Discovery publishes original letters on all areas of rational drug design and discovery including medicinal chemistry, in-silico drug design, combinatorial chemistry, high-throughput screening, drug targets, and structure-activity relationships. The emphasis will be on publishing quality papers very rapidly. Letters will be processed rapidly by taking full advantage of Internet technology for both the submission and review of manuscripts. The journal is essential reading to all pharmaceutical scientists involved in research in drug design and discovery.

Publisher: Bentham Science Publishers

Volume 2, Number 4, June 2005
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Book review

Graphical Abstracts
pp. i-v(1)

Review article

Cytostatic and Cytotoxic Activity of Synthetic Diterpene Derivatives Obtained from (-)-Kaur-9(11), 16-Dien-19-Oic Acid Against Human Cancer Cell Lines
pp. 255-259(5)
Authors: Alonso, Randolph; Gomis, Heidi; Taddei, Antonieta; Sajo, Cristina

Synthesis and Properties of Two Antineoplastic Methanesulfonate Agents Utilizing Folic Acid and Triethanolamine
pp. 260-265(6)
Author: Bartzatt, R. L.

Prostate-Apoptosis-Response-Gene-4: Biological Properties and their Potential Therapeutic Exploitation in Hematological Malignancies
pp. 266-273(8)
Authors: Boehrer, Simone; Nowak, Daniel; Hoelzer, Dieter; Mitrou, Paris S.; Chow, Kai U.

Targeting the G2/M Transition for Antitumor Therapy
pp. 274-281(8)
Authors: Yuan, J.; Strebhardt, K.

Computational Studies of 1-Hydrazinophthalazine (Hydralazine) as Antineoplasic Agent. Docking Studies on Methyltransferase
pp. 282-286(5)
Authors: Angeles, Enrique; HugoVazquez-Valadez, Victor; Vazquez-Valadez, Oscar; Velazquez-Sanchez, Ana M.; Ramirez, Alberto; Martinez, Luisa; Diaz-Barriga, Sandra; Romero-Rojas, Andres; Cabrera, Gustavo; Lopez-Castanares, Rafael; Duenas-Gonzalez, Alfonso

A Quantitative Structure-Activity Relationship Study on Some Na+ and K+ Channel Blockers: Role of Molecular Connectivity Index
pp. 287-290(4)
Authors: Gupta, S. P.; Paleti, Anitha; Mekapati, S. B.; Nagappa, A. N.; Kumaran, S.

Synthesis of a Spiro D-Proline Analogue Bearing D-Fructose
pp. 291-293(3)
Authors: Cipolla, Laura; Redaelli, Cristina; Nicotra, Francesco

Novel Benzo[1,2-c]1,2,5-Oxadiazole N-Oxide Derivatives as Antichagasic Agents: Chemical and Biological Studies
pp. 294-301(8)
Authors: Olea-Azar, Claudio; Rigol, Carolina; Mendizabal, Fernando; Cerecetto, Hugo; Maio, Rossanna D.; Gonzalez, Mercedes; Porcal, Williams; Morello, Antonio; Repetto, Yolanda; Maya, Juan D.i.e.g.o.

Development of Polyfluorophenyltropanes: Potential Probes for 19F Magnetic Resonance Imaging (MRI) and Spectroscopy (MRS) Assessments of the Dopamine Transporter
pp. 302-306(5)
Authors: Zhang, Ao; Kula, Nora S.; Zhang, Kehong; Baldessarini, Ross J.; Kaufman, Marc J.; Renshaw, Perry F.; Neumeyer, John L.

Synthesis of Azetidin-2-One Derivatives as Inhibitor of Secretory Phospholipase A2 with Anti-Inflammatory Activity
pp. 307-310(4)
Authors: Yerigeri, Mayur C.; Murari, Satish K.; Mohammed, Salahuddin; Math, Shanta K.S.; Thimmaiah, Kuntebommanahalli N.; Vishwanath, Bannikuppe S.a.n.n.a.n.a.i.k.

Pituitary Adenylate Cyclase Activating Polypeptide in Animal Models of Neurodegenerative Disorders - Implications for Huntington and Parkinson's Diseases
pp. 311-315(5)
Authors: Reglodi, D.; Tamas, A.; Somogyvari-Vigh, A.

Cytoprotection by Melatonin, Precursors and Metabolites in an In Vitro Model of Neurotoxicity Induced by Okadaic Acid
pp. 316-321(6)
Authors: Tunez, I.; Drucker-Colin, R.; Munoz, M. C.; Montilla, P.

Computational Characterization of a Series of Eicosanoids
pp. 322-328(7)
Authors: Gracon, A. S.A.; Pernecky, S. J.; Milletti, M. C.; Park, J.- A.; Yuan, Y.; Kim, H.

Synthesis and Cyclooxygenase-2 (COX-2) Inhibiting Properties of 1,5- Diarylpyrazoles Possessing N-Substitution on the Sulfonamide (-SO2NH2) Moiety†
pp. 329-340(12)
Authors: Pal, Manojit; Veeramaneni, Venugopal R.; Kumar, Sanjeev; Vangoori, Akhila; Mullangi, Ramesh; Misra, Parimal; Rajjak, Shaikh A.b.d.u.l.; Lohray, Vidya B.; Casturi, Seshagiri R.a.o.; Yeleswarapu, Koteswar R.a.o.

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Key:
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Free Trial Content - Free Trial Content
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