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Publisher: Bentham Science Publishers

Volume 2, Number 1, January 2005
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Book review

Editorial
pp. iv-iv(1)
Authors: Reitz, Allen B.; Atta-ur-Rahman,; Kordik, Cheryl P.; Choudhary, M. I.

Contributors
pp. viii-xiii(1)

Review article

Novel Inhibitors of HIV Integrase: The Discovery of Potential Anti-HIV Therapeutic Agents
pp. 3-20(18)
Author: Nair, Vasu

Macrolide Antibiotics: Binding Site, Mechanism of Action, Resistance
pp. 21-35(15)
Authors: Gaynor, Marne; Mankin, Alexander S.

Potential New Targets for Antithrombotic Therapy
pp. 37-48(12)
Authors: Gruber, Andras; Hanson, Stephen R.

Potent and Selective A2A Adenosine Receptor Antagonists: Recent Improvements
pp. 49-62(14)
Authors: Cacciari, Barbara; Pastorin, Giorgia; Moro, Stefano; Spalluto, Giampiero

Updating the Dual Role of Brain Nitric Oxide in Neurodegeneration / Neuroprotection: Understanding Molecular Mechanisms to Devise Drug Approaches
pp. 63-109(47)
Authors: Contestabile, Antonio; Monti, Barbara; Contestabile, Andrea; Ciani, Elisabetta

Effect of Genetic Background on Ionotropic Glutamate Receptor and Neurotrophin Biology: Synaptic Connectivity and Function in Neurological Disease
pp. 111-132(22)
Authors: Barnes, Gregory N.; Slevin, John T.

Medical Marijuana in CNS Disorders
pp. 133-159(27)
Authors: Drysdale, Alison J.; Platt, Bettina

Obesity and Diabetes Gene Discovery Approaches
pp. 161-182(22)
Authors: Walder, Ken; Segal, David; Jowett, Jeremy; Blangero, John; Collier, Greg R.

Understanding the Molecular Mechanism of Action of Estrogen Receptor Modulators
pp. 183-231(49)
Authors: Meegan, Mary J.; Lloyd, David G.

Recent Advances in Peroxisome Proliferator- Activated Receptor Science
pp. 233-251(19)
Authors: Shearer, Barry G.; Hoekstra, William J.

Recent Developments in the Synthesis and Evaluation of Glucose Analog Inhibitors of Glycogen Phosphorylases as Potential Antidiabetic Agents
pp. 253-272(20)
Authors: Somsak, Laszlo; Nagy, Veronika; Hadady, Zsuzsa; Felfoldi, Nora; Docsa, Tibor; Gergely, Pal

Regulation by Nicotine of Food Intake and Body Weight: Implications for Obesity Treatment
pp. 273-297(25)
Authors: Li, Ming D.; Kane, Justin K.; Konu, Ozlen

Histone Deacetylase Inhibitors: From Chromatin Remodelling to Experimental Cancer Therapeutics
pp. 299-315(17)
Authors: Arts, Janine; Schepper, Stefanie d.; Emelen, Kristof V.a.n.

Radiogenetic Therapy Using Radiation-Responsive Gene Promoters
pp. 317-330(14)
Authors: Marples, Brian; Greco, Olga; Joiner, Michael C.; Scott, Simon D.

Inhibitors of Farnesyltransferase and Geranylgeranyltransferase-I for Antitumor Therapy: Substrate-Based Design, Conformational Constraint and Biological Activity
pp. 331-355(25)
Authors: Dinsmore, Christopher J.; Bell, Ian M.

Enediyne Natural Products: Biosynthesis and Prospect Towards Engineering Novel Antitumor Agents
pp. 357-369(13)
Authors: Shen, Ben; Liu, Wen; Nonaka, Koichi

Heparin Derivatives and Semisynthetic Biotechnological Heparins as Angiogenesis Inhibitors
pp. 371-391(21)
Authors: Presta, Marco; Leali, Daria; Stabile, Helena; Ronca, Roberto; Camozzi, Maura; Moroni, Emanuela; Nicoli, Stefania; Liekens, Sandra; Rusnati, Marco

VIP and Drug Design 2004
pp. 393-415(23)
Authors: Gozes, Illana; Furman, Sharon

Chemical Genomics-Based Target Mining and Validation of Biologically Active Small Molecules
pp. 417-430(14)
Author: Kwon, Ho J.

Ethnobotany and Natural Products: The Search for New Molecules, New Treatments of Old Diseases or a Better Understanding of Indigenous Cultures?
pp. 431-450(20)
Author: Heinrich, Michael

Natural Killer T Cells as Targets for Therapeutic Intervention in Autoimmune Diseases
pp. 451-484(34)
Authors: Wilson, Michael T.; Kaer, Luc V.

Combinatorial Synthesis of Small Molecule Libraries by Microwave Technology
pp. 485-510(26)
Author: Sun, Chung-Ming

Pharmacophore Discovery - Lessons Learned
pp. 511-532(22)
Author: Drie, John H.v.a.n.

Drug Discovery Today
pp. 533-543(11)
Authors: Schwardt, Oliver; Cutting, Brian; Kolb, Hartmuth; Ernst, Beat

Theoretical Property Predictions
pp. 545-570(26)
Author: Livingstone, David J.

Prediction of Drug Metabolism: The Case of Cytochrome P450 2D6
pp. 571-586(16)
Author: E.Vermeulen, Nico P.

Addendum

Subject Index to Volume 2
pp. 587-606(20)
Author: Bentham Science Publishers,

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