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Publisher: Bentham Science Publishers

Articles

Editorial [ Structure-Based Drug Design in the 21st Century ]
pp. i-iii(3)
Authors: Atta-ur-Rahman; Iqbal Choudhary, M.; Caldwell, Gary W.; Player, Mark R.

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Alpha-Helix Mimetics: Progress Toward Effective Modulation of Protein-Protein Complexes
pp. 5-44(40)
Authors: Parks, Daniel J.; Player, Mark R.

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Structures of HIV Protease Guide Inhibitor Design to Overcome Drug Resistance
pp. 45-62(18)
Authors: Weber, Irene T.; Kovalevsky, Andrey Y.; Harrison, Robert W.

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Structure and Function of G Protein-Coupled Receptors Studied Using Sequence Analysis,Molecular Modeling and Receptor Engineering:Adenosine Receptors
pp. 63-79(17)
Authors: Costanzi, Stefano; Ivanov, Andrei A.; Tikhonova, Irina G.; Jacobson, Kenneth A.

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Virtual Docking:How Are We Doing And How Can We Improve?
pp. 81-103(23)
Authors: DesJarlais, Renee L.; Cummings, Maxwell D.; Gibbs, Alan C.

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Fragment-Based Lead Discovery by NMR
pp. 105-119(15)
Author: Schade, Markus

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Targeting Drug Resistant Mutations Using Novel Binding Interactions - Lessons Learned from Abl-T315I and their Implications in Drug Design
pp. 121-144(24)
Authors: Noronha, Glenn; Cao, Jianguo; Chow, Chun; Dneprovskaia, Elena; Hwang, Linda; Lohse, Dan; Ching Mak, Chi; McPherson, Andrew; Fine, Richard M.; Kang, Xinshan; Klebansky, Boris; Palanki, Moorthy S.S.; Pathak, Ved P.; Renick, Joel; Soll, Richard; Zeng, Binqi

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Fragment-Based Approaches to Lead Discovery
pp. 171-202(32)
Authors: Wyss, Daniel F.; Eaton, Hugh L.

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Recent Advances in Structure-Based Design of Nuclear Hormone Receptors
pp. 203-224(22)
Authors: Magolda, Ronald L.; Somers, William S.; Unwalla, Rayomand J.

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Structure-Based Drug Development Against Malaria
pp. 225-255(31)
Authors: Buchholz, Kathrin; Mwongela Mailu, Boniface; Heiner Schirmer, R.; Becker, Katja

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Scoring Functions for Virtual Screening
pp. 317-379(63)
Authors: Spyrakis, Francesca; Kellogg, Glen E.; Amadasi, Alessio; Cozzini, Pietro

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Reactivators of Tabun-Inhibited Acetylcholinesterase:Structure-Biological Activity Relationship
pp. 381-394(14)
Authors: Kuca, Kamil; Jun, Daniel; Musilek, Kamil; Bajgar, Jiri

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Peptide Diversity in Drug Discovery
pp. 395-432(38)
Authors: Brennan, Marian P.; Cox, Dermot; Chubb, Anthony J.

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Protection of Neurovascular Injury by Vasoprotective Agents: A Novel Therapeutic Strategy for Ischemic Brain Edema
pp. 433-454(22)
Authors: Han, Feng; Shioda, Norifumi; Shirasaki, Yasufumi; Fukunaga, Kohji

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Protein Flexibility and Mobility in Structure-Based Drug Design
pp. 455-476(22)
Authors: Ahmed, Aqeel; Kazemi, Sina; Gohlke, Holger

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Structure-Based Virtual Screening
pp. 477-502(26)
Authors: Polgar, Timea; Keseru, Gyorgy M.

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Antibody-Drug Conjugates in Targeted Therapy for Cancer
pp. 525-537(13)
Authors: Tang, Ruoping; Cohen, Simy; Legrand, Ollivier; Marie, Jean-Pierre

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Structure-Activity Relationships in Peptides:from Modelling to Rational Drug Design
pp. 539-558(20)
Authors: Benedetti, Ettore; Pedone, Carlo; Saviano, Michele

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Rational Design Strategies for the Development of Synthetic Quinoline and Acridine Based Antimalarials
pp. 559-609(51)
Authors: Dascombe, Michael J.; B. Drew, Michael G.; Evans, Philip G.; D. Ismail, Fyaz M.

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Contributors
pp. 611-617(7)

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Subject Index
pp. 619-634(16)

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