Bacterial L-Arabinose Isomerases: Industrial Application for D-Tagatose Production
Authors: Boudebbouze, Samira; Maguin, Emmanuelle; Rhimi, Moez
Source: Recent Patents on DNA & Gene Sequences, Volume 5, Number 3, December 2011 , pp. 194-201(8)
Publisher: Bentham Science Publishers
Abstract:D-tagatose is a natural monosaccharide with a low caloric value and has an anti-hyperglycemiant effect. This hexose has potential applications both in pharmaceutical and agro-food industries. However, the use of D-tagatose remains limited by its production cost. Many production procedures including chemical and biological processes were developed and patented. The most profitable production way is based on the use of L-arabinose isomerase which allows the manufacture of D-tagatose with an attractive rate. Future developments are focused on the generation of L-arabinose isomerases having biochemical properties satisfying the industrial applications. This report provides a brief review of the most recent patents that have been published relating to this area.
Keywords: L-arabinose isomerase; D-tagatose; biotechnological applications; protein engineering; Bacterial L-Arabinose; Isomerases; sugars; thermophile strains; calorie substrate; anti-biofilm; peripheral blood monocyte cells (PBMCs); hGH-N polypeptides; disulfide bridges; thermophilic arabinose; dimerization; acid-labile subunit
Document Type: Research article
Publication date: 2011-12-01
- Recent Patents on DNA and Gene Sequences publishes review articles by experts on recent patents on DNA and gene sequences. A selection of important and recent patents in the field is also included in the journal. The journal is essential reading for all researchers involved in applied molecular biology.