Bacterial L-Arabinose Isomerases: Industrial Application for D-Tagatose Production
Abstract:D-tagatose is a natural monosaccharide with a low caloric value and has an anti-hyperglycemiant effect. This hexose has potential applications both in pharmaceutical and agro-food industries. However, the use of D-tagatose remains limited by its production cost. Many production procedures including chemical and biological processes were developed and patented. The most profitable production way is based on the use of L-arabinose isomerase which allows the manufacture of D-tagatose with an attractive rate. Future developments are focused on the generation of L-arabinose isomerases having biochemical properties satisfying the industrial applications. This report provides a brief review of the most recent patents that have been published relating to this area.
Keywords: Bacterial L-Arabinose; D-tagatose; Isomerases; L-arabinose isomerase; acid-labile subunit; anti-biofilm; biotechnological applications; calorie substrate; dimerization; disulfide bridges; hGH-N polypeptides; peripheral blood monocyte cells (PBMCs); protein engineering; sugars; thermophile strains; thermophilic arabinose
Document Type: Research Article
Publication date: December 1, 2011
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