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Gene Patents in the Primary Prevention of Vascular Diseases

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Abstract:

Atherosclerosis is the leading cause of death and disability in the developed world. Despite the use of aggressive therapies, a high morbidity and mortality with vascular origin persists. It is necessary to find new therapeutic targets complementing the existing ones to solve this sanitary problem. Basic and clinical investigation into many of the diverse aspects of cardiovascular drug discovery employs varied approaches aimed at determining physiologic and pathophysiologic efficacy of candidate agents for therapeutic utility with the ultimate hope of identifying those agents capable of exerting salutary influence upon cardiac and vascular tissues. We collected the articles published based on gene patenting in the primary prevention of vascular diseases. Promising compounds may then be used for prophylactic cardiovascular protection and for the treatment of various disorders including endothelial dysfunction, inflammation, hypertension and dyslipidaemia.





Keywords: Gene patents; atherosclerosis; dyslipidaemia; endothelial dysfunction; hypertension; vascular disease

Document Type: Research Article

DOI: http://dx.doi.org/10.2174/187221508786241693

Publication date: November 1, 2008

More about this publication?
  • Recent Patents on DNA and Gene Sequences publishes review articles by experts on recent patents on DNA and gene sequences. A selection of important and recent patents in the field is also included in the journal. The journal is essential reading for all researchers involved in applied molecular biology.
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