Recent Patents of Gene Sequences Relative to DNA Polymerases
Abstract:Organisms with DNA genomes encode one or more DNA polymerases that are essential enzymes for chromosome replication, DNA repair and recombination. The ability of DNA polymerases to copy DNA templates has been exploited in a variety of in vitro reactions to sequence, amplify, mutate, label and recombine DNA, and in several other applications that are fundamental to molecular biology. Because natural DNA polymerases may have activities that interfere with in vitro applications or their substrate specificity is too narrow, DNA polymerases have been modified for specific applications. Patents are reviewed here on natural and variant DNA polymerases and their uses.
Keywords: DNA amplification (PCR); DNA labeling; DNA polymerase applications; DNA polymerases; DNA recombination; DNA replication; DNA sequencing; Evolving DNA polymerases; Mutating DNA; Variant DNA polymerases
Document Type: Research Article
Publication date: November 1, 2008
- Recent Patents on DNA and Gene Sequences publishes review articles by experts on recent patents on DNA and gene sequences. A selection of important and recent patents in the field is also included in the journal. The journal is essential reading for all researchers involved in applied molecular biology.