Skip to main content

Recent Patents on the Identification and Clinical Application of microRNAs and Target Genes

Buy Article:

$105.00 plus tax (Refund Policy)

MicroRNAs (miRNAs) are an abundant class of small non-coding regulatory RNAs. By pairing with target mRNAs, miRNAs could inhibit translation and/or lead to the cleavage or decay of mRNAs targeted. Due to the broad targeting ability, miRNAs play critical roles in regulating diverse biological processes, including cell proliferation, differentiation and apoptosis. In normal cells, the expression of tumor-suppressor genes and oncogenes is tightly regulated by complex gene regulatory networks consisting of miRNAs. The disruption of such networks could lead to various kinds of diseases, including cancers. Due to the biological and medical significances, miRNA studies become an extremely active field, and the number of patent applications related to miRNAs is growing exponentially. This review summarizes some recent published patents and relevant research advances on computational prediction and experimental identification of miRNAs and their targets, along with the potential applications of miRNAs on cancer diagnosis and treatment.

No References
No Citations
No Supplementary Data
No Data/Media
No Metrics

Keywords: algorithms; cancer; gene expression; miRNAs; microarray; oncogene; quantitation; real-time PCR; targets; tumor suppressor gene

Document Type: Research Article

Publication date: 2007-06-01

More about this publication?
  • Recent Patents on DNA and Gene Sequences publishes review articles by experts on recent patents on DNA and gene sequences. A selection of important and recent patents in the field is also included in the journal. The journal is essential reading for all researchers involved in applied molecular biology.
  • Access Key
  • Free content
  • Partial Free content
  • New content
  • Open access content
  • Partial Open access content
  • Subscribed content
  • Partial Subscribed content
  • Free trial content
Cookie Policy
Cookie Policy
Ingenta Connect website makes use of cookies so as to keep track of data that you have filled in. I am Happy with this Find out more