Home >> Drug Metabolism Letters, Volume 5, Number 4
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Drug Metabolism Letters publishes short papers on major advances in all areas of drug metabolism and disposition. The emphasis will be on publishing quality papers very rapidly. Letters will be processed rapidly by taking full advantage of the Internet technology for both the submission and review of manuscripts. The journal covers the following areas:

In vitro systems including CYP-450; enzyme induction and inhibition; drug-drug interactions and enzyme kinetics; pharmacokinetics, toxicokinetics, species scaling and extrapolations; P-glycoprotein and transport carriers; target organ toxicity and interindividual variability; drug metabolism and disposition studies; extrahepatic metabolism; phase I and phase II metabolism; recent developments for the identification of drug metabolites, reactive intermediate and glutathione conjugates.

Publisher: Bentham Science Publishers

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Volume 5, Number 4, December 2011

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Articles

Systematic and Pairwise Analysis of the Effects of Aromatic Halogenation and Trifluoromethyl Substitution on Human Liver Microsomal Clearance
pp. 232-242(11)
Authors: Sun, Hao; E. Keefer, Christopher; O. Scott, Dennis

Effect of Oxidative Stress on the Pharmacokinetics of Clomipramine in Rats Treated with Ferric-Nitrilotriacetate
pp. 243-252(10)
Authors: Kobuchi, Shinji; Fukushima, Keizo; Aoyama, Hiroaki; Matsuda, Tatsuma; Ito, Yukako; Sugioka, Nobuyuki; Takada, Kanji

A Non-acidic Sulfaphenazole Analog Demonstrating High Intrinsic Clearance and Selectivity by Canine CYP2C21
pp. 253-258(6)
Authors: W. Locuson, Charles; F. Alfaro, Josh; J. Zaya, Matthew; Billen, Denis; A. White, Julie; P. Jones, Jeffrey

A Luminescence Study of the Interaction of Sulfobutylether-β-Cyclodextrin with Rutin
pp. 259-266(8)
Authors: Wu, Min; Song, Zhenghua; Zhang, Jingjing

Toxicophoric and Metabolic In Silico Evaluation of Benzimidazole and Phenylbenzamide Derivatives with Potential Application as Anticancer Agents
pp. 267-275(9)
Authors: Barreto da Silva, Vinicius; Machado Leopoldino, Andreia; Anthony Taft, Carlton; Henrique Tomich de Paula da Silva, Carlos

Study of Degradation Behavior of Baicalin during Simulative Blood Sample Processing with Solid Phase Extraction Technology and Identification of the Degradation Product
pp. 276-279(4)
Authors: Chen, Lihong; Wang, Qiang; Tang, Yuping

Investigation of the Metabolism of Rufinamide and Its Interaction with Valproate
pp. 280-289(10)
Authors: T. Williams, Eric; Eric Carlson, J.; George Lai, W.; Nancy Wong, Y.; Yoshimura, Tsutomu; J. Critchley, David; Narurkar, Milind

Gender Effects on Rat Metabolism of AMG 900, an Orally Available Small Molecule Aurora Kinase Inhibitor
pp. 290-297(8)
Authors: Waldon, Daniel; Berry, Loren; Jasmine Lin, Min-Hwa; Schenkel, Laurie; Steven Hollis, L.; Zhao, Zhiyang

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