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Nanoparticles for Gene Delivery: A Brief Patent Review

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Abstract:

Gene therapy, as therapeutic treatment to genetic or acquired diseases, is attracting much interest in the research community, leading to noteworthy developments over the past two decades. Nonviral vectors have recently received an increasing attention in order to overcome the safety problems of viral counterpart. Nanoparticles with their special characteristics such as small particle size, large surface area and the capability of changing their surface properties have numerous advantages compared with other gene delivery systems. This article reviews the advances of nanoparticles in patents for gene delivery and emphasizes methods to promote gene transfection efficiency.





Keywords: Gene delivery; gene transfection efficiency; nanoparticles; nanoparticles modification

Document Type: Research Article

DOI: http://dx.doi.org/10.2174/187221109788452258

Publication date: June 1, 2009

More about this publication?
  • Recent Patents on Drug Delivery and Formulation publishes review articles by experts on recent patents on drug delivery and formulation. A selection of important and recent patents on drug delivery and formulation is also included in the journal. The journal is essential reading for all researchers involved in the fields of drug delivery and formulation.
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