Trends in Pharmaceutical Taste Masking Technologies: A Patent Review

Authors: Ayenew, Zelalem; Puri, Vibha; Kumar, Lokesh; Bansal, Arvind K.

Source: Recent Patents on Drug Delivery & Formulation, Volume 3, Number 1, January 2009 , pp. 26-39(14)

Publisher: Bentham Science Publishers

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Abstract:

According to the year 2003 survey of pediatricians by the American Association of Pediatrics, unpleasant taste was the biggest barrier for completing treatment in pediatrics. The field of taste masking of active pharmaceutical ingredients(API) has been continuously evolving with varied technologies and new excipients. The article reviews the trends in taste masking technologies by studying the current state of the art patent database for the span of year 1997 to 2007. The worldwide database of European patent office(http://ep.espacenet.com) was employed to collect the patents and patent applications. It also discusses the possible reasons for the change of preferences in the taste masking technologies with time. The prime factors critical to the selection of an optimal taste masking technique such as the extent of drug bitterness, solubility, particle characteristics, dosage form and dose are briefly discussed.

Keywords: Taste masking; sweeteners; taste suppressants; taste potentiators

Document Type: Research article

DOI: http://dx.doi.org/10.2174/187221109787158364

Publication date: 2009-01-01

More about this publication?

Recent Patents on Drug Delivery and Formulation publishes review articles by experts on recent patents on drug delivery and formulation. A selection of important and recent patents on drug delivery and formulation is also included in the journal. The journal is essential reading for all researchers involved in the fields of drug delivery and formulation.