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Vascular disease is the commonest cause of death in Westernized countries and its incidence is on the increase in developing countries. It follows that considerable research is directed at establishing effective treatment for acute vascular events. Long-term treatment has also received considerable attention (e.g. for symptomatic relief). Furthermore, effective prevention, whether primary or secondary, is backed by the findings of several landmark trials.

Vascular disease is a complex field with primary care physicians and nurse practitioners as well as several specialties involved. The latter include cardiology, vascular and cardio thoracic surgery, general medicine, radiology, clinical pharmacology and neurology (stroke units). Current Vascular Pharmacology will publish reviews to update all those concerned with the treatment of vascular disease. For example, reviews commenting on recently published trials or new drugs will be included. In addition to clinically relevant topics we will consider 'research-based' reviews dealing with future developments and potential drug targets. Therefore, another function of Current Vascular Pharmacology is to bridge the gap between clinical practice and ongoing research.

Debates will also be encouraged in the correspondence section of this journal.

Publisher: Bentham Science Publishers

Volume 2, Number 2, April 2004

Review article

Prostaglandin J2 Family and the Cardiovascular System
pp. 103-114(12)
Authors: Sasaguri, Toshiyuki; Miwa, Yoshikazu

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Endothelial Dysfunction in Heart Failure: Mechanisms and Therapeutic Approaches
pp. 115-124(10)
Authors: Bauersachs, Johann; Schafer, Andreas

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Role of the Giant Elastic Protein Titin in the Frank-Starling Mechanism of the Heart
pp. 135-139(5)
Authors: Fukuda, Norio; Granzier, Henk

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The Role of Vascular Cell Senescence in Atherosclerosis: Antisenescence as a Novel Therapeutic Strategy for Vascular Aging
pp. 141-148(8)
Authors: Minamino, Tohru; Miyauchi, Hideyuki; Yoshida, Toshihiko; Tateno, Kaoru; Komuro, Issei

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The Role of the Chemokines in Myocardial Ischemia and Reperfusion
pp. 163-174(12)
Author: Frangogiannis, Nikolaos G.

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Passive Smoking and Coronary Heart Disease
pp. 175-182(8)
Authors: Leone, Aurelio; Giannini, Danilo; Bellotto, Chiara; Balbarini, Alberto

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Gene Therapy Approaches for the Prevention of Restenosis
pp. 183-189(7)
Authors: Kopp, Christoph W.; Martin, Rainer d.

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Regulation of Blood Flow by Prostaglandins
pp. 191-197(7)
Authors: Boushel, R.; Langberg, H.; Risum, N.; Kjaer, M.

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