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Publisher: Bentham Science Publishers

Volume 11, Number 4, February 2011

Articles

Predicting Clearance in Humans from In Vitro Data
pp. 334-339(6)
Author: Scott Obach, R.

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In-Silico ADME Models: A General Assessment of their Utility in Drug Discovery Applications
pp. 358-381(24)
Authors: Paul Gleeson, M.; Hersey, Anne; Hannongbua, Supa

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Pharmacodynamic-Pharmacokinetic Integration as a Guide to Medicinal Chemistry
pp. 404-418(15)
Authors: Gabrielsson, Johan; Fjellstrom, Ola; Ulander, Johan; Rowley, Michael; H. Van Der Graaf, Piet

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Strategies and Chemical Design Approaches to Reduce the Potential for Formation of Reactive Metabolic Species
pp. 419-449(31)
Authors: A. Argikar, Upendra; B. Mangold, James; P. Harriman, Shawn

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Do We Need to Optimize Plasma Protein and Tissue Binding in Drug Discovery?
pp. 450-466(17)
Authors: Liu, Xingrong; Chen, Cuiping; E.C.A. Hop, Cornelis

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Discovery and ADMET: Where Are We Now
pp. 467-481(15)
Author: A. Smith, Dennis

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