Current Topics in Medicinal Chemistry

Editorial [Hot Topic: Fragment-Based Drug Discovery Approaches (Guest Editors: Jeffrey Albert and Judd Berman)]
pp. 1543-1543(1)
Authors: Albert, Jeffrey; Berman, Judd

Fragment-Based Drug Discovery: What has it Achieved so Far?
pp. 1544-1567(24)
Authors: Alex, Alexander A.; Flocco, Maria M.

The SeeDs Approach: Integrating Fragments into Drug Discovery
pp. 1568-1581(14)
Authors: Hubbard, Roderick E.; Davis, Ben; Chen, Ijen; Drysdale, Martin J.

Fragment Based Drug Discovery Using Fluorescence Correlation Spectroscopy Techniques: Challenges and Solutions
pp. 1582-1591(10)
Authors: Hesterkamp, T.; Barker, J.; Davenport, A.; Whittaker, M.

Practical Aspects of NMR-based Fragment Discovery
pp. 1592-1599(8)
Authors: Zartler, Edward R.; Mo, Huaping

An Integrated Approach to Fragment-Based Lead Generation:Philosophy, Strategy and Case Studies from AstraZeneca's Drug Discovery Programmes
pp. 1600-1629(30)
Authors: Albert, Jeffrey S.; Blomberg, Niklas; Breeze, Alexander L.; Brown, Alastair J.H.; Burrows, Jeremy N.; Edwards, Philip D.; Folmer, Rutger H.A.; Geschwindner, Stefan; Griffen, Ed J.; Kenny, Peter W.; Nowak, Thorsten; Olsson, Lise-Lotte; Sanganee, Hitesh; Shapiro, Adam B.

SPR-based Fragment Screening: Advantages and Applications
pp. 1630-1642(13)
Authors: Neumann, T.; Junker, H-D.; Schmidt, K.; Sekul, R.

Molecule of the Month
pp. 1643-1643(1)
Authors: Bolinger, Julie D.; Lindsley, Craig W.