Current Topics in Medicinal Chemistry

Editorial [Hot Topic: Small Molecule Inhibition of Protein-Protein Interaction:An Emerging Paradigm in Drug Design (Guest Editor: Craig W. Lindsley)]
pp. 921-921(1)
Author: Lindsley, Craig W.

Protein-Protein Interaction Inhibitors: Small Molecules from Screening Techniques
pp. 922-927(6)
Authors: Fletcher, Steven; Hamilton, Andrew D.

Scaffolds for Blocking Protein-Protein Interactions
pp. 928-942(15)
Authors: Hershberger, Stefan J.; Lee, Song-Gil; Chmielewski, Jean

Towards Drugs Targeting Multiple Proteins in a Systems Biology Approach
pp. 943-951(9)
Authors: Keskin, O.; Gursoy, A.; Ma, B.; Nussinov, R.

Small Molecule Protein-Protein Inhibitors for the p53-MDM2 Interaction
pp. 952-960(9)
Authors: Dudkina, Anna S.; Lindsley, Craig W.

Small Molecule Inhibition of the Bcl-XL-BH3 Protein-Protein Interaction: Proof-of-Concept of an In Vivo Chemopotentiator ABT-737
pp. 961-965(5)
Author: Stauffer, Shaun R.

Small Molecule Inhibitors of the XIAP Protein-Protein Interaction
pp. 966-971(6)
Author: Rajapakse, Hemaka A.

Disruption of the Keap1-Containing Ubiquitination Complex as an Antioxidant Therapy
pp. 972-978(7)
Authors: Kern, Jonathan T.; Hannink, Mark; Fred Hess, J.

Editorial [Hot Topic: Computational Approaches in Medicinal Chemistry and Drug Discovery (Guest Editor: Dr. Fredy Sussman)]
pp. 979-979(1)
Author: Sussman, Fredy

The Search for Drug Leads Targeted to the β -Secretase: An Example of the Roles of Computer Assisted Approaches in Drug Discovery
pp. 980-990(11)
Authors: Carmen Villaverde, M.; Gonzalez-Louro, Lucia; Sussman, Fredy

Structural Models of Class A G Protein-Coupled Receptors as a Tool for Drug Design: Insights on Transmembrane Bundle Plasticity
pp. 991-998(8)
Authors: Deupi, Xavier; Dolker, Nicole; Luz Lopez-Rodriguez, Maria; Campillo, Mercedes; Ballesteros, Juan A.; Pardo, Leonardo

Trp/Met/Phe Hot Spots in Protein-Protein Interactions: Potential Targets in Drug Design
pp. 999-1005(7)
Authors: Ma, Buyong; Nussinov, Ruth

Ligand Docking and Structure-based Virtual Screening in Drug Discovery
pp. 1006-1014(9)
Authors: Cavasotto, Claudio N.; W. Orry, Andrew J.

Medicinal Chemistry and Bioinformatics - Current Trends in Drugs Discovery with Networks Topological Indices
pp. 1015-1029(15)
Authors: Gonzalez-Diaz, Humberto; Vilar, Santiago; Santana, Lourdes; Uriarte, Eugenio

Structure Based Drug Design for HIV Protease: From Molecular Modeling to Cheminformatics
pp. 1030-1038(9)
Authors: Volarath, Patra; Harrison, Robert W.; Weber, Irene T.

Molecule of the Month
pp. 1039-1039(1)
Authors: Nathan Daniels, R.; Lindsley, Craig W.