Current Topics in Medicinal Chemistry

Editorial [Hot Topic: Novel Cancer Therapeutic Targets (Guest Editor: George Hartman)]
pp. 107-107(1)
Author: Hartman, George D.

The Akt/PKB Family of Protein Kinases: A Review of Small Molecule Inhibitors and Progress Towards Target Validation
pp. 109-125(17)
Authors: Barnett, Stanley F.; Bilodeau, Mark T.; Lindsley, Craig W.

Mitotic Kinesins: Prospects for Antimitotic Drug Discovery
pp. 127-145(19)
Authors: Bergnes, Gustave; Brejc, Katjusa; Belmont, Lisa

The Hedgehog Signaling Pathway as a Target for Anticancer Drug Discovery
pp. 147-157(11)
Authors: Borzillo, Gary V.; Lippa, Blaise

Small Molecule Inhibitors of p53/MDM2 Interaction
pp. 159-165(7)
Authors: Fotouhi, Nader; Graves, Bradford

Recent Advances in the Development of Selective Small Molecule Inhibitors for Cyclin-Dependent Kinases
pp. 167-179(13)
Authors: Hirai, Hiroshi; Kawanishi, Nobuhiko; Iwasawa, Yoshikazu

Progress in the Discovery of Polo-like Kinase Inhibitors
pp. 181-197(17)
Authors: McInnes, Campbell; Mezna, Mokdad; Fischer, Peter M.

Progress in the Development of Selective Inhibitors of Aurora Kinases
pp. 199-213(15)
Authors: Mortlock, Andrew; Keen, Nicholas J.; Jung, Frederic H.; Heron, Nicola M.; Foote, Kevin M.; Wilkinson, Robert; Green, Stephen

Progress Towards Therapeutic Small Molecule MEK Inhibitors for Use in Cancer Therapy
pp. 215-229(15)
Authors: Wallace, Eli M.; Lyssikatos, Joseph P.; Yeh, Tammie; Winkler, James D.; Koch, Kevin