Current Topics in Medicinal Chemistry

Preface
pp. i-i(1)
Author: Caldwell, G.W.

The New Pre-Preclinical Paradigm: Compound Optimization in Early and Late Phase Drug Discovery
pp. 353-366(14)
Authors: Caldwell, G.W.; Ritchie, D.M.; Masucci, J.A.; Hageman, W.; Yan, Z.

Strategies for Absorption Screening in Drug Discovery and Development
pp. 367-383(17)
Authors: Bohets, H.; Annaert, P.; Mannens, G.; van beijterveldt, L.; Anciaux, K.; Verboven, P.; Meuldermans, W.; Lavrijsen, K.

Assessing the Absorption of New Pharmaceuticals
pp. 385-401(17)
Author: Hidalgo, I.J.

Metabolism Profiling, and Cytochrome P450 Inhibition & Induction in Drug Discovery
pp. 403-425(23)
Authors: Yan, Z.; Caldwell, G.W.

Nuclear Magnetic Resonance as a Tool in Drug Discovery, Metabolism and Disposition
pp. 427-441(15)
Authors: Pochapsky, S.S.; Pochapsky, T.C.

Tailoring Bioanalysis for PK Studies Supporting Drug Discovery
pp. 443-461(19)
Authors: Timmerman, P.M.M.B.L.; Vries, R.; Ingelse, B.A.

The Use of On-line and Off-line Chromatographic Extraction Techniques coupled with Mass Spectrometry for Support of In Vivo and In Vitro Assays in Drug Discovery
pp. 463-471(9)
Authors: Masucci, J.A.; Caldwell, G.W.; Jones, W.J.; Juzwin, S.J.; Sasso, P.J.; Evangelisto, M.