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In recent years a breakthrough has occurred in our understanding of the molecular pathomechanisms of human diseases whereby most of our diseases are related to intra and intercellular communication disorders. The concept of signal transduction therapy has got into the front line of modern drug research, and a multidisciplinary approach is being used to identify and treat signaling disorders.

The aim of this journal is to publish timely in-depth reviews as well as original papers in the field of signal transduction therapy. Thematic issues will also be published to cover selected areas of signal transduction therapy. Coverage of the field will include genomics, proteomics, medicinal chemistry and the relevant diseases involved in signaling e.g. cancer, neurodegenerative and inflammatory diseases.

Current Signal Transduction Therapy is an essential journal for all involved in drug design and discovery.

Publisher: Bentham Science Publishers

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Volume 4, Number 3, 2009

Articles

Cancer Invasion and Metastasis: Discovering New Targets For Diagnosis and Therapeutics
pp. 152-161(10)
Authors: Alessandro, Riccardo; Fontana, Simona; De Leo, Giacomo

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Hypoxia Inducible Factor-1 as a Therapeutic Target in Cerebral Ischemia
pp. 162-173(12)
Authors: Aguilera, Penelope; Vazquez-Contreras, Edgar; Gomez-Martínez, Carlos D.; Cardenas, Maria E. C.

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When BMP Signalling Goes Wrong: The Intracellular and Molecular Mechanisms of BMP Signalling in Cancer
pp. 174-195(22)
Authors: Bokobza, Sivan M.; Ye, Lin; Jiang, Wen Guo

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Paralysation of HIV Without Impairing Other Cells
pp. 196-200(5)
Authors: Vaezzadeh, Majid; Saeidi, Mohammadreza

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Targeting JAK/STAT Signaling Pathway in Inflammatory Diseases
pp. 201-221(21)
Authors: Malemud, Charles J.; Pearlman, Eric

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The Inhibitory Effect of Cyclosporine A and Prednisolone on Both Cytotoxic CD8+ T Cells and CD4+CD25+ Regulatory T Cells
pp. 222-233(12)
Authors: Fei, Fei; Yu, Yingzhe; Schmitt, Anita; Rojewski, Markus T.; Chen, Baoan; Gotz, Marlies; Guillaume, Philippe; Bunjes, Donald; Schmitt, Michael

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