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Understanding Stem Cell-Mediated Brain Repair Through Neuroimaging

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Abstract:

Transplantation of stem cells into the damaged brain can lead to behavioral recovery. However, at present, the mechanisms by which these cells exert their beneficial effects are still poorly understood. Survival, migration and differentiation are but a few of the factors that are thought to be involved in stem cell-mediated brain repair. It is hoped that neuroimaging, by MRI and PET, will provide serial in vivo assessments of transplanted cells that can lead to a greater understanding of the mechanisms involved in brain repair.





Keywords: Fluorescence; chemical exchange saturation transfer (CEST); magnetic resonance imaging; mapping; neurodegenerative disease; transplanted cells

Document Type: Research Article

DOI: https://doi.org/10.2174/157488806775269106

Publication date: 2006-01-01

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  • Current Stem Cell Research & Therapy publishes frontier reviews on all aspects of basic research on stem cells and their uses in clinical therapy. The journal's aim is to publish the highest quality review articles in the field. The journal is essential reading for all researchers and clinicians involved in stem cells.
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