Upper Airway Resistance Syndrome

Authors: Guilleminault, Christian; Ramar, Kannan

Source: Current Respiratory Medicine Reviews, Volume 4, Number 1, February 2008 , pp. 23-28(6)

Publisher: Bentham Science Publishers

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Abstract:

Upper Airway Resistance Syndrome (UARS) was initially used to describe a group of patients who were sleepy but did not meet the diagnostic criteria of obstructive sleep apnea syndrome (OSAS). Since the original description, controversy and ambiguity of this disorder have lead to limited amounts of adequate data and studies. The incidence, prevalence, natural history, and morbidity of this disorder are not well known, and the diagnosis of UARS remains a controversial issue. Advances in technology have lead to measurement of sensitive polysomnographic variables that may aid in effectively identifying this disorder, distinguishing it from OSAS. Recognition of patients with UARS is important because although these patients are symptomatic, they may not present with the same symptoms as patients with OSAS. Treatment options are available that may benefit patients with UARS. This article reviews the pathophysiology, diagnosis, clinical picture and management of UARS.

Keywords: obstructive sleep apnea syndrome; airway pressure; EEG pattern; continuous positive airway pressure; NREM sleep

Document Type: Research article

DOI: http://dx.doi.org/10.2174/157339808783497882

Publication date: 2008-02-01

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Current Respiratory Medicine Reviews publishes frontier reviews on all the latest advances on respiratory diseases and its related areas e.g. pharmacology, pathogenesis, clinical care, and therapy. The journal's aim is to publish the highest quality review articles dedicated to clinical research in the field. The journal is essential reading for all researchers and clinicians in respiratory medicine.