Optimal Treatment of Severe Community-Acquired Pneumonia

Authors: Grant W. Waterer,; Marcos I. Restrepo,

Source: Current Respiratory Medicine Reviews, Volume 3, Number 3, August 2007 , pp. 233-239(7)

Publisher: Bentham Science Publishers

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Abstract:

Community-acquired pneumonia (CAP) is associated with significant morbidity and mortality and is the most common cause of death from infectious diseases. Severe CAP (SCAP) patients that required ICU admission carry the highest mortality rates. Multiple sets of clinical practice guidelines have been published in the past few years addressing the treatment of CAP, and they all agree that CAP patients admitted to the hospital represent a major concern, and appropriate empiric therapy should be instituted to improve clinical outcomes. The purpose of this article is to review the current literature regarding the optimal empiric selection of antibiotic therapy for patients with SCAP. In addition emphasis on the empiric and direct therapy will be made on patients with bacteremic pneumococcal pneumonia.

Keywords: Pneumonia; antibiotics; S. pneumoniae

Document Type: Research article

DOI: http://dx.doi.org/10.2174/157339807781387553

Publication date: 2007-08-01

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Current Respiratory Medicine Reviews publishes frontier reviews on all the latest advances on respiratory diseases and its related areas e.g. pharmacology, pathogenesis, clinical care, and therapy. The journal's aim is to publish the highest quality review articles dedicated to clinical research in the field. The journal is essential reading for all researchers and clinicians in respiratory medicine.