Bronchiolitis Obliterans-Organizing Pneumonia and Related Conditions in Adult Patients

Authors: Dentale, Nicola¹; Poletti, Venerino¹; Manfredi, Roberto¹; Chiodo, Francesco¹

Source: Current Respiratory Medicine Reviews, Volume 1, Number 2, June 2005 , pp. 147-157(11)

Publisher: Bentham Science Publishers

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Abstract:

Bronchiolitis obliterans and organizing pneumonia (BOOP) represent complex clinical syndromes expressing a similar morphologic pattern, which are observed in a variety of lung diseases. In this view, the Authors report on the clinical and diagnostic profile, radiological features, laboratory and histopathological findings, and management issues of these broad-spectrum pulmonary disorders. Idiopathic forms, infectious disease-associated features, complications of solid organ transplant recipients and bone marrow recipients, collagen vascular- and bowel inflammatory-related forms, the role of drugs and that of irritating and toxic inhalants, and more infrequent ethiologies (which are able to support a bronchiolitis obliterans-organizing pneumonia and related conditions), all these items are thoroughly discussed on the ground of our own experience in this field, and an updated literature review.

Keywords: bronchiolitis obliterans; organizing pneumonia; clinical and diagnostic features; classification; management; outcome

Document Type: Review article

DOI: 10.2174/1573398054023055

Affiliations: 1: Infectious Diseases, University of Bologna, S. Orsola Hospital, Via Massarenti 11, I-40138 Bologna, Italy.

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