Parkinson's Disease Dementia

Authors: Robottom, Bradley J.; Weiner, William J.

Source: Current Psychiatry Reviews, Volume 5, Number 3, August 2009 , pp. 218-225(8)

Publisher: Bentham Science Publishers

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Abstract:

Parkinson's disease (PD) is the second most common neurodegenerative illness diagnosed in the United States. Dementia is recognized to be common in PD, occurring in 19-78&percnt of patients depending upon the definition used. The cognitive syndrome of Parkinson's disease dementia is predominantly one of executive dysfunction, and it has a profile that is distinct from Alzheimer's dementia. Neuropsychiatric problems frequently accompany Parkinson's disease dementia and lead to considerable therapeutic challenges. This review focuses on the epidemiology, clinical characteristics, pathology, neuroimaging, diagnosis, and treatment of Parkinson's disease dementia.

Keywords: Parkinson's disease; dementia; Dementia with Lewy bodies; acetylcholinesterase inhibitors; neuropsychiatry; cognitive dysfunction

Document Type: Research article

Publication date: 2009-08-01

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Current Psychiatry Reviews publishes frontier reviews on all the latest advances on clinical psychiatry and its related areas e.g. pharmacology, epidemiology, clinical care, and therapy. The journal's aim is to publish the highest quality review articles dedicated to clinical research in the field. The journal is essential reading for all clinicians, psychiatrists and researchers in psychiatry.