Managing the Suicidal Risk in Pregnant Women with Severe and Persistent Psychiatric Disorder: Focus on Antisuicidal Drugs and Somatic Interventions

Author: Gentile, Salvatore

Source: Current Psychiatry Reviews, Volume 4, Number 3, August 2008 , pp. 169-184(16)

Publisher: Bentham Science Publishers

Abstract:

Suicide remains a significant public issue. Several concordant information exists suggesting that patients diagnosed with severe and persistent psychiatric disorder (SPPD) show relatively higher rates of deaths by suicide compared with patients suffering from other mental illness. In particular, recent researches have demonstrated that, in pregnant women with history of SPPD, a percentage ranging from 13.1% to 33.0% of mothers may have suicidal ideation. Both psychopathological and social specificities of women with SPPD must force clinicians to consider any suicidal expression shown by these mothers as a signal of possible high-lethality suicide attempts. Because of the vast majority of maternal suicidal deaths due to psychiatric disorder usually occur before week 20 of gestation, the necessity exists to analyze and summarize published literature information on the teratogenic risk of antisuicidal drugs and somatic treatments also associated with the property to reduce the rate of self-aggressive behaviors, in order to identify the safest option to treat suicidal risk during early pregnancy. Further, the difficulties of managing the suicidal risk during the last stages of pregnancy are briefly summarized.

Keywords: Clozapine; electroconvulsive therapy; lithium; pregnancy; serotonin reuptake inhibitors; suicidal risk

Document Type: Research article

Publication date: 2008-08-01

More about this publication?

• Current Psychiatry Reviews publishes frontier reviews on all the latest advances on clinical psychiatry and its related areas e.g. pharmacology, epidemiology, clinical care, and therapy. The journal's aim is to publish the highest quality review articles dedicated to clinical research in the field. The journal is essential reading for all clinicians, psychiatrists and researchers in psychiatry.

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