Nanotechnology and Nanomedicine: Going Small Means Aiming Big

Authors: Kumar Teli, Mahesh; Mutalik, Srinivas; Rajanikant, G.K.

Source: Current Pharmaceutical Design, Volume 16, Number 16, June 2010 , pp. 1882-1892(11)

Publisher: Bentham Science Publishers

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Abstract:

Nanotechnology is an emerging branch of science for designing tools and devices of size 1 to 100 nm with specific function at the cellular, atomic and molecular levels. The concept of employing nanotechnology in biomedical research and clinical practice is best known as nanomedicine. Nanomedicine is an upcoming field that could potentially make a major impact to human health. Nanomaterials are increasingly used in diagnostics, imaging and targeted drug delivery. Nanotechnology will assist the integration of diagnostics/imaging with therapeutics and facilitates the development of personalized medicine, i.e. prescription of specific medications best suited for an individual. This review provides an integrated overview of application of nanotechnology based molecular diagnostics and drug delivery in the development of nanomedicine and ultimately personalized medicine. Finally, we identify critical gaps in our knowledge of nanoparticle toxicity and how these gaps need to be evaluated to enable nanotechnology to transit safely from bench to bedside.

Keywords: Nanotechnology; nanomedicine; personalized medicine; nanodiagnostics; nanomaterials; nanotoxicology

Document Type: Research article

DOI: http://dx.doi.org/10.2174/138161210791208992

Affiliations: 1: Assistant Professor, School of Biotechnology, National Institute of Technology Calicut, Calicut 673601, India.

Publication date: 2010-06-01

More about this publication?
  • Current Pharmaceutical Design publishes timely in-depth reviews covering all aspects of current research in rational drug design. Each issue is devoted to a single major therapeutic area. A Guest Editor who is an acknowledged authority in a therapeutic field has solicits for each issue comprehensive and timely reviews from leading researchers in the pharmaceutical industry and academia.

    Each thematic issue of Current Pharmaceutical Design covers all subject areas of major importance to modern drug design, including: medicinal chemistry, pharmacology, drug targets and disease mechanism.
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