@article {Martin:June 2007:1381-6128:1751,
	author = "Martin, J.",
	author = "Collot-Teixeira, S.",
	author = "McGregor, L.",
	author = "McGregor, J. L.",
	title = "The Dialogue Between Endothelial Cells and Monocytes/Macrophages in Vascular Syndromes",
	journal = "Current Pharmaceutical Design",
	volume = "13",
	year = "June 2007",
	abstract = "The aim of this chapter is to present and identify potential pharmacological targets in endothelial cell-monocyte interactions leading to vascular syndrome and involving inflammation, coagulation, vascular remodelling and thrombosis. Increasing evidence is indicating that endothelial cells play a key role in atherothombosis by their capacity to attract, bind and allow the extravasation of monocytes to sites of inflammation. Surface expression and/or activation of constituent cell adhesion molecules (for e.g. P-selectin, E-selectin, ICAM-1, and VCAM-1) on endothelial cells together with chemokines such as CXCL8 (IL-8), Platelet-activating factor (PAF), CCL2 and CCL5 (Table 1) allow the rolling, adhesion and extravasation of monocytes. This review focuses on pharmacological targets implicated in endothelial cells interactions with monocytes/macrophages in vascular disease states and on cutting edge genomic tools for the identification and characterization of such targets.",
	pages = "1751-1759(9)",
	url = "http://www.ingentaconnect.com/content/ben/cpd/2007/00000013/00000017/art00004"
	doi = "doi:10.2174/138161207780831248"
}