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Current Pharmaceutical Design publishes timely in-depth reviews covering all aspects of current research in rational drug design. Each issue is devoted to a single major therapeutic area. A Guest Editor who is an acknowledged authority in a therapeutic field has solicits for each issue comprehensive and timely reviews from leading researchers in the pharmaceutical industry and academia.

Each thematic issue of Current Pharmaceutical Design covers all subject areas of major importance to modern drug design, including: medicinal chemistry, pharmacology, drug targets and disease mechanism.

Publisher: Bentham Science Publishers

Volume 12, Number 24, August 2006
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Articles

Editorial [ The Wide Roles of Cytokines During Evolution Executive Editors: M. de Eguileor and E. Ottaviani ]
pp. 2993-2995(3)
Authors: de Eguileor, Magda; Ottaviani, Enzo

Phylogeny and Genetic Code: Evolution and Conservation
pp. 2997-3013(17)
Author: Lanzavecchia, G.

The Cell Type-Specific Signal Proteins (Pheromones) of Protozoan Ciliates
pp. 3015-3024(10)
Authors: Luporini, P.; Vallesi, A.; Alimenti, C.; Ortenzi, C.

Cytokines and Invertebrates: TGF-β and PDGF
pp. 3025-3031(7)
Authors: Franchini, A.; Malagoli, D.; Ottaviani, E.

Hematopoietic Cell Formation in Leech Wound Healing
pp. 3033-3041(9)
Authors: Grimaldi, A.; Tettamanti, G.; Perletti, G.; Valvassori, R.; de Eguileor, M.

Innate Immunity in Lophotrochozoans: The Annelids
pp. 3043-3050(8)
Authors: Salzet, Michel; Tasiemski, Aurelie; Cooper, Edwin

Advances in Fish Cytokine Biology Give Clues to the Evolution of a Complex Network
pp. 3051-3069(19)
Authors: Bird, S.; Zou, J.; Secombes, C. J.

Biological Activity of Cytokines: An Evolutionary Perspective
pp. 3071-3081(11)
Authors: Scapigliati, G.; Buonocore, F.; Mazzini, M.

Avian Cytokines - An Overview
pp. 3083-3099(17)
Authors: Giansanti, F.; Giardi, M. F.; Botti, D.

Cytokines and Chemokines as Regulators of Angiogenesis in Health and Disease
pp. 3101-3115(15)
Authors: Benelli, R.; Lorusso, G.; Albini, A.; Noonan, D. M.

Distinctive Cellular Roles for Novel Protein Kinase C Isoenzymes
pp. 3117-3133(17)
Authors: Perletti, G.; Terrian, D. M.

Cannabinoids, Immune System and Cytokine Network
pp. 3135-3146(12)
Authors: Massi, P.; Vaccani, A.; Parolaro, D.

Frailty of Older Age: The Role of the Endocrine - Immune Interaction
pp. 3147-3159(13)
Authors: Paganelli, R.; Di Iorio, A.; Cherubini, A.; Lauretani, F.; Mussi, C.; Volpato, S.; Abate, M.; Abate, G.; Ferrucci, L.

Inflamm-Aging, Cytokines and Aging: State of the Art, New Hypotheses on the Role of Mitochondria and New Perspectives from Systems Biology
pp. 3161-3171(11)
Authors: Salvioli, S.; Capri, M.; Valensin, S.; Tieri, P.; Monti, D.; Ottaviani, E.; Franceschi, C.

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