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Current Pharmaceutical Design publishes timely in-depth reviews covering all aspects of current research in rational drug design. Each issue is devoted to a single major therapeutic area. A Guest Editor who is an acknowledged authority in a therapeutic field has solicits for each issue comprehensive and timely reviews from leading researchers in the pharmaceutical industry and academia.

Each thematic issue of Current Pharmaceutical Design covers all subject areas of major importance to modern drug design, including: medicinal chemistry, pharmacology, drug targets and disease mechanism.

Publisher: Bentham Science Publishers

Volume 11, Number 21, August 2005

Book review

Review article

Mechanism of Local Anesthetic Drug Action on Voltage-Gated Sodium Channels
pp. 2671-2686(16)
Authors: Fozzard, H. A.; Lee, P. J.; Lipkind, G. M.

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Activation and Activators of TRPV1 and Their Pharmaceutical Implication
pp. 2687-2698(12)
Authors: Suh, Young-Ger; Oh, Uhtaek

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Insulin Secretagogues, Sulfonylurea Receptors and KATP Channels
pp. 2699-2716(18)
Authors: Bryan, J.; Crane, A.; Vila-Carriles, W. H.; Babenko, A. P.; Aguilar-Bryan, L.

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Ion Channel Defects in Idiopathic Epilepsies
pp. 2737-2752(16)
Authors: Lerche, Holger; Weber, Yvonne G.; Jurkat-Rott, Karin; Lehmann-Horn, Frank

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The TRPM Cation Channels in the Immune Context
pp. 2765-2778(14)
Authors: Schmitz, C.; Perraud, A.- L.

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Beyond Single Pathway Inhibition: MEK Inhibitors as a Platform for the Development of Pharmacological Combinations with Synergistic Anti-Leukemic Effects
pp. 2779-2795(17)
Authors: Milella, M.; Precupanu, C. M.; Gregorj, C.; Ricciardi, M. R.; Petrucci, M. T.; Kornblau, S. M.; Tafuri, A.; Andreeff, M.

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