The Emerging Pharmacology of TRPM8 Channels: Hidden Therapeutic Potential Underneath a Cold Surface
Keywords: A fibers; AMTB; Asp802; C-fibers; Calcium Imaging Microscopy; Cold; DRG neurons; HEK293 cells; Leu1009; MWCmodel; Patch-Clamp Electrophysiology; S4-S5 linker; SKF96365; Ser9; TRPM8 Channels; TRPM8 agonist; TRPM8 gene; TRPM8 modulators; TRPM8-expressing neurons; TRPV1; Thr17; Transient receptor potential melastatin; Tyr745; WS-12; Y745H mutant; bladder urothelium; breast adenocarcinoma; citronellal; cold allodynia; cold nociception; desensitization; detrusor overactivity; geraniol; hippocampal neurons; human prostate carcinoma; linalool; male urogenital tract; melanoma; menthol; menthol affinity; neuroendocrine tumor; pain; peripheral sensory neurons; prostate cancer; prostate epithelium; putative phosphorylation sites; rat myocytes; thermoreceptor; trigeminal ganglia; unmyelinated afferents; vasomotor responses; voltage clamp errors; voltage-gated potassium (Kv) channels
Document Type: Research Article
Publication date: 01 January 2011
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