Recombinant Expression in Moderate Halophiles
Authors: Tokunaga, Masao; Arakawa, Tsutomu; Tokunaga, Hiroko
Source: Current Pharmaceutical Biotechnology, Volume 11, Number 3, April 2010 , pp. 259-266(8)
Publisher: Bentham Science Publishers
Abstract:A novel expression of recombinant proteins was developed using moderate halophiles that accumulate osmolytes and hence provide cytoplasmic environments where osmolyte-driven folding can take place. Promoters and selection marker were developed for high expression of foreign proteins. Examples are given for expression of bacterial nucleoside diphosphate kinase and human serine racemase.
Document Type: Research Article
Publication date: April 1, 2010
- Current Pharmaceutical Biotechnology aims to cover all the latest and outstanding developments in Pharmaceutical Biotechnology. Each issue of the journal contains a series of timely in-depth reviews written by leaders in the field covering a range of current topics in both pre-clinical and clinical areas of Pharmaceutical Biotechnology. Current Pharmaceutical Biotechnology is an essential journal for academic, clinical, government and pharmaceutical scientists who wish to be kept informed and up-to-date with the latest and most important developments.