Nutritional and Therapeutic Potential of Spirulina

Authors: Khan, Z.¹; Bhadouria, P.¹; Bisen, P. S.¹

Source: Current Pharmaceutical Biotechnology, Volume 6, Number 5, October 2005 , pp. 373-379(7)

Publisher: Bentham Science Publishers

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Abstract:

Spirulina, a filamentous cyanobacterium, possesses diverse biological activities and nutritional significance due to high concentration of natural nutrients, having bio-modulatory and immuno-modulatory functions. Different Spirulina preparations influence immune system viz. increase phagocytic activity of macrophages, stimulating the production of antibodies and cytokines, increase accumulation of NK cells into tissue and activation and mobilization of T and B cells. Spirulina have also shown to perform regulatory role on lipid and carbohydrate metabolism by exhibiting glucose and lipid profile correcting activity in experimental animals and in diabetic patients. Preparations have been found to be active against several enveloped viruses including herpes virus, cytomegalovirus, influenza virus and HIV. They are capable to inhibit carcinogenesis due to anti-oxidant properties that protect tissues and also reduce toxicity of liver, kidney and testes.

Keywords: spirulina platensis; ca-sp; sulpholipid; cyanovirin-n; phycocyanin; beta-carotene; hiv; immunomodulatory

Document Type: Review article

DOI: 10.2174/138920105774370607

Affiliations: 1: Department of Biotechnology, J.C. Bose Institute of Life Sciences, Bundelkhand University, Jhansi 284128, U.P., India.

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