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Current Pharmaceutical Biotechnology aims to cover all the latest and outstanding developments in Pharmaceutical Biotechnology. Each issue of the journal contains a series of timely in-depth reviews written by leaders in the field covering a range of current topics in both pre-clinical and clinical areas of Pharmaceutical Biotechnology. Current Pharmaceutical Biotechnology is an essential journal for academic, clinical, government and pharmaceutical scientists who wish to be kept informed and up-to-date with the latest and most important developments.

Publisher: Bentham Science Publishers

Volume 5, Number 2, April 2004
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Book review

Foreword
pp. i-ii(1)
Authors: Zeno Foldes-Papp; Jorg Enderlein; Jerker Widengren; Masataka Kinjo

Preface [Hot Topic: The Way Down from Single Genes and Proteins to Single Molecules (Guest Editors: Z. Foldes-Papp, J. Enderlein, J. Widengren and M. Kinjo)]
pp. iii-iii(1)
Author: Rudolf Rigler

Review article

The LSM 510 META - ConfoCor 2 System: An Integrated Imaging and Spectroscopic Platform for Single-Molecule Detection
pp. 135-154(20)
Authors: Klaus Weisshart; Volker Jungel; Stephen J. Briddon

Art and Artefacts of Fluorescence Correlation Spectroscopy
pp. 155-161(7)
Authors: Jorg Enderlein; Ingo Gregor; Digambara Patra; Jorg Fitter

Counting and Behavior of an Individual Fluorescent Molecule without Hydrodynamic Flow, Immobilization, or Photon Count Statistics
pp. 163-172(10)
Authors: Zeno Foldes-Papp; Gerd Baumann; Ulrike Demel; Gernot P. Tilz

Towards Sorting of Biolibraries Using Single-Molecule Fluorescence Detection Techniques
pp. 173-179(7)
Authors: Antonie J.W.G. Visser; Beno H. Kunst; Hans Keller; Arjen Schots

Phenotypic Screening for Pharmaceuticals Using Tissue Constructs
pp. 181-189(9)
Authors: T. Wakatsuki; J. A. Fee; E. L. Elson

Direct Gene Expression Analysis
pp. 191-197(7)
Authors: Holger Winter; Kerstin Korn; Rudolf Rigler

DNA Measurements by Using Fluorescence Correlation Spectroscopy and Two-Color Fluorescence Cross Correlation Spectroscopy
pp. 199-204(6)
Authors: Takuya Takagi; Hiroaki Kii; Masataka Kinjo

Ligand-Receptor Interactions in Live Cells by Fluorescence Correlation Spectroscopy
pp. 205-212(8)
Author: Aladdin Pramanik

Analyzing for Co-Localization of Proteins at a Cell Membrane
pp. 213-220(8)
Authors: Anja Nohe; Nils O. Petersen

Enzyme Assays for Confocal Single Molecule Spectroscopy
pp. 221-229(9)
Authors: M. Jahnz; P. Schwille

Parallel Confocal Detection of Single Biomolecules Using Diffractive Optics and Integrated Detector Units
pp. 231-241(11)
Authors: H. Blom; M. Gosch

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