Growth Factor Delivery to Re-Engineer Periodontal Tissues

Authors: Anusaksathien O.; Giannobile W.V.

Source: Current Pharmaceutical Biotechnology, Volume 3, Number 2, June 2002 , pp. 129-139(11)

Publisher: Bentham Science Publishers

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Abstract:

Repair of tooth-supporting structures destroyed by the chronic inflammatory disease periodontitis is a major goal of oral therapy. The field of tissue engineering combines materials science and biology to repair tissues and organs. Periodontal tissue engineering has been achieved with limited success by the utilization of guiding tissue (cell occlusive) membranes and bone grafting techniques. Over the past decade investigators have begun to utilize signaling molecules such as growth factors to restore lost tooth support due to periodontitis, the most common bone disease affecting humans. This review will provide information on the status of growth factor therapies being applied in periodontology to treat advanced alveolar bone loss.

Keywords: igfs; periodontal; growth factor; gfs; gtr

Language: English

Document Type: Review article

DOI: http://dx.doi.org/10.2174/1389201023378391

Publication date: 2002-06-01

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Current Pharmaceutical Biotechnology aims to cover all the latest and outstanding developments in Pharmaceutical Biotechnology. Each issue of the journal contains a series of timely in-depth reviews written by leaders in the field covering a range of current topics in both pre-clinical and clinical areas of Pharmaceutical Biotechnology. Current Pharmaceutical Biotechnology is an essential journal for academic, clinical, government and pharmaceutical scientists who wish to be kept informed and up-to-date with the latest and most important developments.