@article {Diefenbach:October 2005:1570-1646:225,
	author = "Diefenbach, E.",
	author = "Cunningham, A. L.",
	author = "Diefenbach, R. J.",
	title = "Defining Viral Protein Interactomes Using the Yeast Two-Hybrid Assay",
	journal = "Current Proteomics",
	volume = "2",
	year = "October 2005",
	abstract = "The yeast two-hybrid assay has proved a powerful tool in identifying and characterising binary protein-protein interactions. Not only can it be used to map interacting protein domains, it can also be used to screen cDNA libraries with a desired bait to identify novel binding partners. A number of factors including ease of use, cost effectiveness and suitability for high throughput analysis have made yeast-two hybrid one of the assays of choice for defining protein-protein interaction networks or interactomes for a range of organisms. The focus of this review is on the definition of viral interactomes using the yeast two-hybrid assay and the relevance of such studies to our understanding of viral pathogenesis.",
	pages = "225-231(7)",
	url = "http://www.ingentaconnect.com/content/ben/cp/2005/00000002/00000003/art00004"
	doi = "doi:10.2174/157016405774641138"
}