Chemistry of Natural Retinoids and Carotenoids: Challenges for the Future

Authors: Valla A.R.; Cartier D.L.; Labia R.

Source: Current Organic Synthesis, Volume 1, Number 2, April 2004 , pp. 167-209(43)

Publisher: Bentham Science Publishers

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Abstract:

Natural retinoids, especially retinol, are present in all living organisms and are known as fundamental mediators for many biological processes. Recently, protective effects of carotenoids against severe diseases have encouraged exhaustive chemical and biochemical researches. The emphasis for the past twenty years has been the stereoselective syntheses of economically important retinoids and carotenoids, such as retinol, retinal, RAs, bgr

-carotene, astaxanthin, lycopene etc.

This review covers the major developments of synthetic chemistry on natural retinoids and carotenoids from 1990 to the present.

Keywords: retinoids; carotenoids; xanthophylls; metabolites; synthesis

Document Type: Review article

DOI: http://dx.doi.org/10.2174/1570179043485394

Affiliations: 1: Laboratoire de Chimie et Biologie des Substances Naturelles, 6 rue de l'Universite 29000 Quimper, France.

Publication date: 2004-04-01

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Current Organic Synthesis publishes in-depth reviews on all areas of synthetic organic chemistry i.e. asymmetric synthesis, organometallic chemistry, novel synthetic approaches to complex organic molecules, carbohydrates, polymers, protein chemistry, DNA chemistry, supramolecular chemistry, molecular recognition and new synthetic methods in organic chemistry. The frontier reviews provide the current state of knowledge in these fields and are written by experts who are internationally known for their eminent research contributions. The journal is essential reading to all synthetic organic chemists. Current Organic Synthesis should prove to be of great interest to synthetic chemists in academia and industry who wish to keep abreast with recent developments in key fields of organic synthesis.