17 O-Isotope Labeling and Hydrogen-Bonded Structure Investigation in Peptides and Polypeptides by Solid State 17 O NMR

Authors: Kuroki S.; Yamauchi K.; Ando I.; Shoji A.; Ozaki T.

Source: Current Organic Chemistry, Volume 5, Number 10, October 2001 , pp. 1001-1015(15)

Publisher: Bentham Science Publishers

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Abstract:

Most recent research works on the hydrogen-bonded structure of solid 17 O-labeled peptides and polypeptides by means of solid-state 17 O NMR are presented. It has been demonstrated that 17 O-labeling andsolid-state 17 O NMR provide useful informations about the hydrogen-bonded structure between the amide oxygen and proton of peptides and polypeptides in the solid state, in addition to 1H, 13C and 15N techniques.

Keywords: labeled peptides; hydrogen-bonded structure

Language: English

Document Type: Review article

DOI: 10.2174/1385272013374914

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