Steroidal Oligoglycosides from the Asteroidea

Authors: Iorrizzi M.; Marino S.De; Zollo F.

Source: Current Organic Chemistry, Volume 5, Number 9, September 2001 , pp. 951-973(23)

Publisher: Bentham Science Publishers

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Abstract:

Starfish extracts have been reported to exhibit a broad spectrum of pharmacological properties, which are related to the presence of typical steroidal oli-goglycosides. In the animal kingdom, these metabolites have only been found in the marine phylum Echinodermata and particularly in the class Asteroidea (sea stars).

This communication offers a general view of steroid oligoglycoside distribution among starfishes and focuses on a number of recent examples, much of these from the authors laboratory, to discuss structural characteristics, biological activities and methods of investigation.

Keywords: Steroidal oligoglycosides; Asteroidea; Asterosaponins; saponins; cyclicsteroidal glycosides; echinaster sepositus; glycosides; polyhysroxysteroids; hmqc-tocsy

Language: English

Document Type: Review article

DOI: 10.2174/1385272013374978

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